D-serine mitigates cell loss associated with temporal lobe epilepsy

Temporal lobe epilepsy (TLE) can be unresponsive to treatment. Here, the authors show that treatment with D-Serine mitigates TLE and acts on neurons and glia, attenuating neuronal loss and reducing astro- and microgliosis in rodents.

Bibliographic Details
Main Authors: Stephen Beesley, Thomas Sullenberger, Kathryn Crotty, Roshan Ailani, Cameron D’Orio, Kimberly Evans, Emmanuel O. Ogunkunle, Michael G. Roper, Sanjay S. Kumar
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18757-2