Enzyme polymorphism in warfarin dose management after pediatric cardiac surgery

Background: Warfarin is an anticoagulant and is widely used for the prevention of thromboembolic events. Genetic variants of the enzymes that metabolize warfarin, i.e. cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1), contribute to differences in patients’ responses to various w...

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Bibliographic Details
Main Authors: Avisa Tabib, Babak Najibi, Mohammad Dalili, Ramin Baghaei, Behzad Poopak
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Research in Cardiovascular Medicine
Subjects:
Online Access:http://www.rcvmonline.com/article.asp?issn=2251-9572;year=2015;volume=4;issue=3;spage=10;epage=10;aulast=Tabib;type=0