Transcriptional regulation of 15-lipoxygenase expression by histone h3 lysine 4 methylation/demethylation.
15-Lipoxygenase-1 (15-LOX-1) oxidizes polyunsaturated fatty acids to a rich spectrum of biologically active metabolites and is implicated in physiological membrane remodelling, inflammation and apoptosis. Its deregulation is involved in the pathogenesis of diverse cancer and immune diseases. Recent...
Main Authors: | Cheng Liu, Dawei Xu, Hongya Han, Yidong Fan, Frida Schain, Zhonghua Xu, Hans-Erik Claesson, Magnus Björkholm, Jan Sjöberg |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3532411?pdf=render |
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