Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis
Aim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoraci...
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doaj-25555b48a95245569aef67a0a4eacabd2020-11-25T01:53:43ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2018-09-01493747754Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysisWessam Abdelrahman Elzayat0Marwa M. Onsy1Mohamed Talaat Ali2Hassan Ali El-Kiki3Rania Ali Hegazy4Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, Egypt; Corresponding author at: Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, El-Manial, 11956 Cairo, Egypt.Diagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptDiagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptDiagnostic and Intervention Radiology Department, Cairo University Hospitals, Kasr Al-Ainy, Cairo, EgyptPediatric Department, Abu El Reesh Hospital, Kasr Al-Ainy, Cairo, EgyptAim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoracic vascular anomalies (22 boys & 18 girls) ranging in age between 6 months and 14 years (mean age 4.58 ± 4.5) were included in this prospective study. Measurements of the thoracic arteries were taken by 3D SSFP NC-MRA & CE-MRA. Image quality was assessed using a four-point score. Pearson's and Spearman's Correlation Coefficients were calculated for correlation analysis while Student's t and Mann-Whitney U tests were used for comparative analysis, Bland-Altman plots were employed to demonstrate the level of agreement between the 2 techniques. Results: Measurements from NC-CMRA images were comparable to those from CE-MRA. All measures highly correlated (r > 0.9), 3D SSFP NC-MRA exhibited a significantly higher image quality score than contrast- enhanced MRA, the mean difference was significantly lower than that of the 3D SSFP; (p-value <0.0001). Conclusion: NC-MRA produced similar and comparable measurements of the thoracic arteries with superior image quality when compared to contrast- enhanced MRA in pediatric congenital heart defects. Keywords: MRI, Thoracic vessels, Congenital hearthttp://www.sciencedirect.com/science/article/pii/S0378603X18300627 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy |
spellingShingle |
Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis The Egyptian Journal of Radiology and Nuclear Medicine |
author_facet |
Wessam Abdelrahman Elzayat Marwa M. Onsy Mohamed Talaat Ali Hassan Ali El-Kiki Rania Ali Hegazy |
author_sort |
Wessam Abdelrahman Elzayat |
title |
Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
title_short |
Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
title_full |
Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
title_fullStr |
Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
title_full_unstemmed |
Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis |
title_sort |
non contrast versus contrast enhanced mri of the great thoracic vessels in pediatric congenital heart disease: a quantitative and qualitative analysis |
publisher |
SpringerOpen |
series |
The Egyptian Journal of Radiology and Nuclear Medicine |
issn |
0378-603X |
publishDate |
2018-09-01 |
description |
Aim: To compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease. Methodology: Forty patients with thoracic vascular anomalies (22 boys & 18 girls) ranging in age between 6 months and 14 years (mean age 4.58 ± 4.5) were included in this prospective study. Measurements of the thoracic arteries were taken by 3D SSFP NC-MRA & CE-MRA. Image quality was assessed using a four-point score. Pearson's and Spearman's Correlation Coefficients were calculated for correlation analysis while Student's t and Mann-Whitney U tests were used for comparative analysis, Bland-Altman plots were employed to demonstrate the level of agreement between the 2 techniques. Results: Measurements from NC-CMRA images were comparable to those from CE-MRA. All measures highly correlated (r > 0.9), 3D SSFP NC-MRA exhibited a significantly higher image quality score than contrast- enhanced MRA, the mean difference was significantly lower than that of the 3D SSFP; (p-value <0.0001). Conclusion: NC-MRA produced similar and comparable measurements of the thoracic arteries with superior image quality when compared to contrast- enhanced MRA in pediatric congenital heart defects. Keywords: MRI, Thoracic vessels, Congenital heart |
url |
http://www.sciencedirect.com/science/article/pii/S0378603X18300627 |
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