Antitumor Effects of Trimethylellagic Acid Isolated From Sanguisorba officinalis L. on Colorectal Cancer via Angiogenesis Inhibition and Apoptosis Induction

Antitumor Effects of Trimethylellagic Acid Isolated From Sanguisorba officinalis L. on Colorectal Cancer via Angiogenesis Inhibition and Apoptosis Induction

Previous studies have demonstrated that tannin could inhibit the proliferation and angiogenesis of cancer cells. However, the mechanism(s) associated with its antitumor effect remains unclear. Here, we investigated the effects of 3,3',4'-trimethylellagic acid (TMEA), a tannin compound isol...

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Bibliographic Details
Main Authors: Chongfei Bai, Yueshan Sun, Xianchao Pan, Jing Yang, Xiaoxuan Li, Anguo Wu, Dalian Qin, Shousong Cao, Wenjun Zou, Jianming Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
3,3',4'-trimethylellagic acid
antitumor effects
antiangiogenesis
cytotoxicity
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01646/full

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