Corneal biomechanics in connective tissue disorders
Purpose: The purpose of this study is to determine the corneal biomechanical properties in patients with connective tissue disorders (CTDs) and compare them with age-matched healthy control. Materials and Methods: In this cross-sectional study, 62 patients (study group) with CTDs and 44 healthy pati...
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Wolters Kluwer Medknow Publications
2021-01-01
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Online Access: | http://www.jcor.in/article.asp?issn=2320-3897;year=2021;volume=9;issue=2;spage=64;epage=66;aulast=Kesarwani |
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doaj-257675e40a4848a79c953a9bfdfee1672021-08-09T09:55:20ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972021-01-0192646610.4103/jcor.jcor_74_20Corneal biomechanics in connective tissue disordersDivya KesarwaniVaibhav Kumar JainRachna AgarwalJaya KaushikKumudini SharmaPurpose: The purpose of this study is to determine the corneal biomechanical properties in patients with connective tissue disorders (CTDs) and compare them with age-matched healthy control. Materials and Methods: In this cross-sectional study, 62 patients (study group) with CTDs and 44 healthy patients (control) were analyzed by Ocular Response Analyzer (Reichert Inc., Depew, N. Y., USA) and Corneal Pachymetry (SP-2000, Tomey, Nagoya, Japan). The right eye of all patients was assessed for corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPc), and Goldmann-correlated intraocular pressure (IOPg), and central corneal thickness (CCT). Results: Mean CH (9.54 ± 1.66 mm Hg [study group] and 10.62 ± 1.21 mm Hg [control]; P = 0.013) and mean CRF (9.95 ± 1.47 mm Hg [study group] and 10.76 ± 1.25 mm Hg [control]; P = 0.040) were significantly different between groups. Mean IOPc, IOPg, and CCT were not significantly different between groups. In the subgroup analysis of study cases (oral steroid versus nonsteroid therapy) of CTDs, CRF which was significantly lower in steroid (9.25 mm Hg) compared nonsteroid therapy (10.20 mm Hg) (P = 0.045), whereas, other parameters such as CCT, CH, IOPc, and IOPg were comparable between the two groups (P ≥ 0.05). Conclusion: CH is altered in CTDs which may be an independent risk factor for glaucoma and might underestimate intraocular pressure so CH is an important consideration in patients with CTDs.shttp://www.jcor.in/article.asp?issn=2320-3897;year=2021;volume=9;issue=2;spage=64;epage=66;aulast=Kesarwaniconnective tissue disorderscorneal biomechanicscorneal hysteresisintraocular pressurerheumatoid |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Divya Kesarwani Vaibhav Kumar Jain Rachna Agarwal Jaya Kaushik Kumudini Sharma |
spellingShingle |
Divya Kesarwani Vaibhav Kumar Jain Rachna Agarwal Jaya Kaushik Kumudini Sharma Corneal biomechanics in connective tissue disorders Journal of Clinical Ophthalmology and Research connective tissue disorders corneal biomechanics corneal hysteresis intraocular pressure rheumatoid |
author_facet |
Divya Kesarwani Vaibhav Kumar Jain Rachna Agarwal Jaya Kaushik Kumudini Sharma |
author_sort |
Divya Kesarwani |
title |
Corneal biomechanics in connective tissue disorders |
title_short |
Corneal biomechanics in connective tissue disorders |
title_full |
Corneal biomechanics in connective tissue disorders |
title_fullStr |
Corneal biomechanics in connective tissue disorders |
title_full_unstemmed |
Corneal biomechanics in connective tissue disorders |
title_sort |
corneal biomechanics in connective tissue disorders |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Clinical Ophthalmology and Research |
issn |
2320-3897 |
publishDate |
2021-01-01 |
description |
Purpose: The purpose of this study is to determine the corneal biomechanical properties in patients with connective tissue disorders (CTDs) and compare them with age-matched healthy control. Materials and Methods: In this cross-sectional study, 62 patients (study group) with CTDs and 44 healthy patients (control) were analyzed by Ocular Response Analyzer (Reichert Inc., Depew, N. Y., USA) and Corneal Pachymetry (SP-2000, Tomey, Nagoya, Japan). The right eye of all patients was assessed for corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPc), and Goldmann-correlated intraocular pressure (IOPg), and central corneal thickness (CCT). Results: Mean CH (9.54 ± 1.66 mm Hg [study group] and 10.62 ± 1.21 mm Hg [control]; P = 0.013) and mean CRF (9.95 ± 1.47 mm Hg [study group] and 10.76 ± 1.25 mm Hg [control]; P = 0.040) were significantly different between groups. Mean IOPc, IOPg, and CCT were not significantly different between groups. In the subgroup analysis of study cases (oral steroid versus nonsteroid therapy) of CTDs, CRF which was significantly lower in steroid (9.25 mm Hg) compared nonsteroid therapy (10.20 mm Hg) (P = 0.045), whereas, other parameters such as CCT, CH, IOPc, and IOPg were comparable between the two groups (P ≥ 0.05). Conclusion: CH is altered in CTDs which may be an independent risk factor for glaucoma and might underestimate intraocular pressure so CH is an important consideration in patients with CTDs.s |
topic |
connective tissue disorders corneal biomechanics corneal hysteresis intraocular pressure rheumatoid |
url |
http://www.jcor.in/article.asp?issn=2320-3897;year=2021;volume=9;issue=2;spage=64;epage=66;aulast=Kesarwani |
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