Novel methods for the encapsulation of meglumine antimoniate into liposomes

Novel methods for the encapsulation of meglumine antimoniate into liposomes

The antimonial drug, meglumine antimoniate, was successfully encapsulated in dehydration-rehydration vesicles and in freeze-dried empty liposomes (FDELs). High encapsulation efficiencies (from 28 to 58%) and low weight ratios of lipids to encapsulated antimony (from 1:0.15 to 1:0.3) were achieved. T...

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Bibliographic Details
Main Authors:	F. Frézard, M.S.M. Michalick, C.F. Soares, C. Demicheli
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2000-07-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	liposomes glucantime meglumine antimoniate leishmaniasis encapsulation
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700016

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