Usual Complication after Radiotherapy of Jaws for Carcinoma: Osteoradionecrosis

• Main Authors: Kartik Dholakia, Rahul Dhanak, Tushar Makwana
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Advances in Human Biology
• Subjects: Osteoradionecrosis; maxilla; mandible; radiotherapy; Pentoxiphylline.
• Online Access: http://www.aihbonline.com/article.asp?issn=2321-8568;year=2014;volume=4;issue=3;spage=77;epage=81;aulast=Dholakia;type=0

Background: Osteoradionecrosis (ORN) is the death of bone due to radiation. The bone dies because of damage to its blood vessels caused by the radiation. Radiation provides high cure rates, but has also called increasing attention to its side effects. Osteoradionecrosis (ORN) is one of the most severe and serious complications of head and neck cancer treatment. A new theory for the pathogenesis of ORN has proposed that damage to bone is caused by radiation-induced fibrosis. Here there is a case which was operated conservatively and after 8 months of follow up no recurrence was observed.