Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction. Methods: Patients who received orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between March 2012 and October...
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doaj-2599da4f84324aeb898e7852c19c58572020-11-24T21:13:48ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372018-06-0124068184Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destructionYan-Fang Duan0Min-Jie Fan1Department of Stomatology, Hancheng People’s Hospital in Shaanxi Province, Hancheng, Shaanxi Province, 715400Department of Ophthalmology & Otorhinolaryngology, Hancheng People's Hospital in Shaanxi Province, Hancheng, Shaanxi Province, 715400Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction. Methods: Patients who received orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between March 2012 and October 2017 were retrospectively studied, and according to the nickeltitanium arch wire materials in history data, the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment, the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment, IL-1毩, IL- 1β, sTREM1 and HMGB1 contents as well as RANKL, 5-LOX, LTB4, TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG, Wnt3a, Runx2, OC, ALP and OCIF mRNA expression were significantly higher than those of control group. Conclusion: Heat-activated nickel-titanium arch wire for orthodontic treatment can be more effective than common nickeltitanium arch wire to reduce the local tissue inflammation and inhibit the bone destruction.http://www.hnykdxxb.com/PDF/201806/20.pdf and according to the nickeltitanium arch wire materials in history datathe patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatmentthe gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatmentIL-1毩IL- 1βsTREM1 and HMGB1 contents as well as RANKL5-LOXLTB4TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPGWnt3aRunx2OCOrthodontic treatmentHeat-activated nickel-titanium arch wireInflammationBone destructionApoptosis |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yan-Fang Duan Min-Jie Fan |
spellingShingle |
Yan-Fang Duan Min-Jie Fan Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction Journal of Hainan Medical University and according to the nickeltitanium arch wire materials in history data the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment IL-1毩 IL- 1β sTREM1 and HMGB1 contents as well as RANKL 5-LOX LTB4 TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG Wnt3a Runx2 OC Orthodontic treatment Heat-activated nickel-titanium arch wire Inflammation Bone destruction Apoptosis |
author_facet |
Yan-Fang Duan Min-Jie Fan |
author_sort |
Yan-Fang Duan |
title |
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
title_short |
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
title_full |
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
title_fullStr |
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
title_full_unstemmed |
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
title_sort |
effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2018-06-01 |
description |
Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic
treatment on local tissue inflammation and bone destruction. Methods: Patients who received
orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between
March 2012 and October 2017 were retrospectively studied, and according to the nickeltitanium arch wire materials in history data, the patients were divided into the experimental
group who used heat-activated nickel-titanium arch wire and the control group who used
common nickel-titanium arch wire. 1 week after treatment, the gingival crevicular fluid was
collected to determine the contents of inflammatory cytokines as well as the mRNA expression
of osteoblast markers and osteoclast markers. Results: 1 week after treatment, IL-1毩, IL-
1β, sTREM1 and HMGB1 contents as well as RANKL, 5-LOX, LTB4, TRACP5b and
ODF mRNA expression in gingival crevicular fluid of experimental group were significantly
lower than those of control group whereas OPG, Wnt3a, Runx2, OC, ALP and OCIF mRNA
expression were significantly higher than those of control group. Conclusion: Heat-activated
nickel-titanium arch wire for orthodontic treatment can be more effective than common nickeltitanium arch wire to reduce the local tissue inflammation and inhibit the bone destruction. |
topic |
and according to the nickeltitanium arch wire materials in history data the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment IL-1毩 IL- 1β sTREM1 and HMGB1 contents as well as RANKL 5-LOX LTB4 TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG Wnt3a Runx2 OC Orthodontic treatment Heat-activated nickel-titanium arch wire Inflammation Bone destruction Apoptosis |
url |
http://www.hnykdxxb.com/PDF/201806/20.pdf |
work_keys_str_mv |
AT yanfangduan effectofheatactivatednickeltitaniumarchwirefororthodontictreatmentonlocaltissueinflammationandbonedestruction AT minjiefan effectofheatactivatednickeltitaniumarchwirefororthodontictreatmentonlocaltissueinflammationandbonedestruction |
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1716748138014834688 |