Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction

Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction. Methods: Patients who received orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between March 2012 and October...

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Main Authors: Yan-Fang Duan, Min-Jie Fan
Format: Article
Language:English
Published: Editorial Board of Journal of Hainan Medical University 2018-06-01
Series:Journal of Hainan Medical University
Subjects:
OC
Online Access:http://www.hnykdxxb.com/PDF/201806/20.pdf
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spelling doaj-2599da4f84324aeb898e7852c19c58572020-11-24T21:13:48ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372018-06-0124068184Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destructionYan-Fang Duan0Min-Jie Fan1Department of Stomatology, Hancheng People’s Hospital in Shaanxi Province, Hancheng, Shaanxi Province, 715400Department of Ophthalmology & Otorhinolaryngology, Hancheng People's Hospital in Shaanxi Province, Hancheng, Shaanxi Province, 715400Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction. Methods: Patients who received orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between March 2012 and October 2017 were retrospectively studied, and according to the nickeltitanium arch wire materials in history data, the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment, the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment, IL-1毩, IL- 1β, sTREM1 and HMGB1 contents as well as RANKL, 5-LOX, LTB4, TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG, Wnt3a, Runx2, OC, ALP and OCIF mRNA expression were significantly higher than those of control group. Conclusion: Heat-activated nickel-titanium arch wire for orthodontic treatment can be more effective than common nickeltitanium arch wire to reduce the local tissue inflammation and inhibit the bone destruction.http://www.hnykdxxb.com/PDF/201806/20.pdf and according to the nickeltitanium arch wire materials in history datathe patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatmentthe gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatmentIL-1毩IL- 1βsTREM1 and HMGB1 contents as well as RANKL5-LOXLTB4TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPGWnt3aRunx2OCOrthodontic treatmentHeat-activated nickel-titanium arch wireInflammationBone destructionApoptosis
collection DOAJ
language English
format Article
sources DOAJ
author Yan-Fang Duan
Min-Jie Fan
spellingShingle Yan-Fang Duan
Min-Jie Fan
Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
Journal of Hainan Medical University
and according to the nickeltitanium arch wire materials in history data
the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment
the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment
IL-1毩
IL- 1β
sTREM1 and HMGB1 contents as well as RANKL
5-LOX
LTB4
TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG
Wnt3a
Runx2
OC
Orthodontic treatment
Heat-activated nickel-titanium arch wire
Inflammation
Bone destruction
Apoptosis
author_facet Yan-Fang Duan
Min-Jie Fan
author_sort Yan-Fang Duan
title Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
title_short Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
title_full Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
title_fullStr Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
title_full_unstemmed Effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
title_sort effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction
publisher Editorial Board of Journal of Hainan Medical University
series Journal of Hainan Medical University
issn 1007-1237
1007-1237
publishDate 2018-06-01
description Objective: To study the effect of heat-activated nickel-titanium arch wire for orthodontic treatment on local tissue inflammation and bone destruction. Methods: Patients who received orthodontic treatment with nickel-titanium arch wire in Hancheng People’s Hospital between March 2012 and October 2017 were retrospectively studied, and according to the nickeltitanium arch wire materials in history data, the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment, the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment, IL-1毩, IL- 1β, sTREM1 and HMGB1 contents as well as RANKL, 5-LOX, LTB4, TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG, Wnt3a, Runx2, OC, ALP and OCIF mRNA expression were significantly higher than those of control group. Conclusion: Heat-activated nickel-titanium arch wire for orthodontic treatment can be more effective than common nickeltitanium arch wire to reduce the local tissue inflammation and inhibit the bone destruction.
topic and according to the nickeltitanium arch wire materials in history data
the patients were divided into the experimental group who used heat-activated nickel-titanium arch wire and the control group who used common nickel-titanium arch wire. 1 week after treatment
the gingival crevicular fluid was collected to determine the contents of inflammatory cytokines as well as the mRNA expression of osteoblast markers and osteoclast markers. Results: 1 week after treatment
IL-1毩
IL- 1β
sTREM1 and HMGB1 contents as well as RANKL
5-LOX
LTB4
TRACP5b and ODF mRNA expression in gingival crevicular fluid of experimental group were significantly lower than those of control group whereas OPG
Wnt3a
Runx2
OC
Orthodontic treatment
Heat-activated nickel-titanium arch wire
Inflammation
Bone destruction
Apoptosis
url http://www.hnykdxxb.com/PDF/201806/20.pdf
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