Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population
The repurposing of the CRISPR/Cas microbial adaptive immune system for gene editing has resulted in an exponential rise in new technologies and promising approaches for treating numerous human diseases. While some of the approaches being currently developed involve ex vivo editing by CRISPR/Cas9, ma...
Main Authors: | Vijaya L. Simhadri, Joseph McGill, Shane McMahon, Junxia Wang, Haiyan Jiang, Zuben E. Sauna |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-09-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050118300603 |
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