Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B.

BACKGROUND/AIMS:The seroclearance of hepatitis B virus (HBV) surface antigen (HBsAg) is regarded as a functional cure of chronic hepatitis B (CHB) although it occurs rarely. Recently, several genome-wide association studies (GWASs) revealed various genetic alterations related to the clinical course...

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Main Authors: Tae Hyung Kim, Eun-Ju Lee, Ji-Hye Choi, Sun Young Yim, Sunwon Lee, Jaewoo Kang, Yoo Ra Lee, Han Ah Lee, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Hyung Joon Yim, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Chang Duck Kim, Hyun Goo Woo, Soon Ho Um
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6033413?pdf=render