Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant

Brazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evalua...

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Main Authors: Jaqueline Gozzi Bordini, Mario Augusto Ono, Melissa Tiemi Hirozawa, Glauco Tironi Garcia, Edio Vizoni, Elisabete Yurie Sataque Ono
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/11/1/33
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spelling doaj-25a7c56b9f584b34946425baaf7b46c42020-11-24T21:41:32ZengMDPI AGToxins2072-66512019-01-011113310.3390/toxins11010033toxins11010033Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing PlantJaqueline Gozzi Bordini0Mario Augusto Ono1Melissa Tiemi Hirozawa2Glauco Tironi Garcia3Edio Vizoni4Elisabete Yurie Sataque Ono5Department of Biochemistry and Biotechnology, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, BrazilDepartment of Pathological Sciences, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, BrazilDepartment of Biochemistry and Biotechnology, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, BrazilG Tironi Garcia Consultoria Técnica—ME, Andirá 86380-000, Paraná, BrazilDepartment of Statistics, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, BrazilDepartment of Biochemistry and Biotechnology, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, BrazilBrazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a relevant criterion for mycotoxin risk assessment. Thus, human exposure to fumonisins were assessed for corn grain and its derivatives (endosperm, cornmeal, and grits; n = 320) sampled from one of the large-scale corn processing plants in Brazil. The total probable daily intake (PDI) for fumonisins in Brazil was 96.9 ng kg−1 body weight day−1, which corresponds to 5% of the provisional maximum tolerable daily intake (PMTDI) of 2000 ng kg−1 b.w. day−1 for fumonisins. In countries that import Brazilian corn, the total PDI is lower in European countries (from 35.7 to 177 ng kg−1 b.w. day−1) and higher in Angola (1553 ng kg−1 b.w. day−1). Taking into account that dietary exposure in populations in Brazil and importing countries was low, the corn-based products were safe for human consumption regarding fumonisins, even for regions with high corn consumption.http://www.mdpi.com/2072-6651/11/1/33food safetydaily intakemycotoxinscornmealendospermexposure
collection DOAJ
language English
format Article
sources DOAJ
author Jaqueline Gozzi Bordini
Mario Augusto Ono
Melissa Tiemi Hirozawa
Glauco Tironi Garcia
Edio Vizoni
Elisabete Yurie Sataque Ono
spellingShingle Jaqueline Gozzi Bordini
Mario Augusto Ono
Melissa Tiemi Hirozawa
Glauco Tironi Garcia
Edio Vizoni
Elisabete Yurie Sataque Ono
Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
Toxins
food safety
daily intake
mycotoxins
cornmeal
endosperm
exposure
author_facet Jaqueline Gozzi Bordini
Mario Augusto Ono
Melissa Tiemi Hirozawa
Glauco Tironi Garcia
Edio Vizoni
Elisabete Yurie Sataque Ono
author_sort Jaqueline Gozzi Bordini
title Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
title_short Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
title_full Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
title_fullStr Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
title_full_unstemmed Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
title_sort safety of corn and corn-based products intended for human consumption concerning fumonisins from a brazilian processing plant
publisher MDPI AG
series Toxins
issn 2072-6651
publishDate 2019-01-01
description Brazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a relevant criterion for mycotoxin risk assessment. Thus, human exposure to fumonisins were assessed for corn grain and its derivatives (endosperm, cornmeal, and grits; n = 320) sampled from one of the large-scale corn processing plants in Brazil. The total probable daily intake (PDI) for fumonisins in Brazil was 96.9 ng kg−1 body weight day−1, which corresponds to 5% of the provisional maximum tolerable daily intake (PMTDI) of 2000 ng kg−1 b.w. day−1 for fumonisins. In countries that import Brazilian corn, the total PDI is lower in European countries (from 35.7 to 177 ng kg−1 b.w. day−1) and higher in Angola (1553 ng kg−1 b.w. day−1). Taking into account that dietary exposure in populations in Brazil and importing countries was low, the corn-based products were safe for human consumption regarding fumonisins, even for regions with high corn consumption.
topic food safety
daily intake
mycotoxins
cornmeal
endosperm
exposure
url http://www.mdpi.com/2072-6651/11/1/33
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