Study on risk factors of hemorrhagic transformation in patients with acute cerebral infarction after non thrombolysis

• Main Authors: Li-Na Ma, Xing Li, Dan Yu
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2018-06-01
• Series: Journal of Hainan Medical University
• Subjects: Acute cerebral infarction; Hemorrhage transformation; Influencing factors; Logistic regression analysis
• Online Access: http://www.hnykdxxb.com/PDF/201806/06.pdf

Objective: To study the risk factors of hemorrhagic transformation in patients with acute cerebral infarction and to analyze the risk factors. Methods: A total of 96 patients with acute cerebral infarction after the thrombolysis in our hospital from June 2016 to December 2017 were selected as the research object. And they were divided into bleeding group 48 cases and hemorrhage transformation group 48 cases according to whether with hemorrhage occurs transformation. Then the lipid metabolism, atrial fibrillation, history of smoking and drinking, history of hypertension and diabetes, blood pressure, treatment time after onset and infarction area of two groups were compared, and the relationship between those factors and the disease were analyzed by the multi-factor Logistic regression analysis. Results: The atrial fibrillation, history of smoking and drinking of two groups had significant differences; The hospital fasting plasma glucose and LDL-C level of two groups had significant differences; the treatment time after onset and infarction area of two groups had significant differences; The multi-factor Logistic regression analysis showed that atrial fibrillation, blood glucose on admission, LDL-C and large area of infarction are the factors affecting the risk of bleeding in patients with acute cerebral infarction transformation. Conclusion: Atrial fibrillation, blood glucose on admission, LDL-C, treatment time after onset and large area of infarction belongs to the patients with acute cerebral infarction after the thrombolysis transformation of bleeding risk factors.