Anosognosia for hemiplegia as a tripartite disconnection syndrome

Anosognosia for hemiplegia as a tripartite disconnection syndrome

The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we w...

Full description

Bibliographic Details
Main Authors: Valentina Pacella, Chris Foulon, Paul M Jenkinson, Michele Scandola, Sara Bertagnoli, Renato Avesani, Aikaterini Fotopoulou, Valentina Moro, Michel Thiebaut de Schotten
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
brain
white matter
stroke
awareness
motor
disconnection
Online Access:https://elifesciences.org/articles/46075
Description
Summary:The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that contribute to AHP, when disconnected or directly damaged: the (i) premotor loop (ii) limbic system, and (iii) ventral attentional network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.
ISSN:2050-084X

Similar Items