Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340

Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340

Abstract Background Accumulating evidence indicates that circular RNAs (circRNAs) act as microRNA (miRNA) sponges to directly inhibit specific miRNAs and alter their ability to regulate gene expression at the post-transcriptional level; this mechanism is believed to occur in various cancers. However...

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Bibliographic Details
Main Authors: Xiangyu Jian, Han He, Jiehong Zhu, Qi Zhang, Zhongxin Zheng, Xiangjing Liang, Liuyan Chen, Meiling Yang, Kaiyue Peng, Zhaowen Zhang, Tengfei Liu, Yaping Ye, Hongli Jiao, Shuyang Wang, Weijie Zhou, Yanqing Ding, Tingting Li
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Molecular Cancer
Subjects:
Has-circ_001680
miR-340
Irinotecan
BMI1
Stem cell
Chemotherapy resistance
Online Access:https://doi.org/10.1186/s12943-020-1134-8

Internet

https://doi.org/10.1186/s12943-020-1134-8

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