VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION

VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION

The article focuses on the results of the investigation of peripheral blood lymphocyte morphofunctional status in healthy volunteers and renal allograft recipients for early postoperative period. Working out noninvasive tests for diagnosis of acute renal allograft rejection based on the measuring of...

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Main Authors: A. V. Vatazin, I. A. Vasilenko, A. L. Valov, V. B. Metelin, E. E. Kruglov, A. Ya. Tsalman
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2009-06-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
renal transplantation
acute allograft rejection
lymphocytes
morphometry
Online Access:https://journal.transpl.ru/vtio/article/view/263
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spelling doaj-25c77a4fced84178ae253bad213055632021-07-29T09:08:27ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov Vestnik Transplantologii i Iskusstvennyh Organov1995-11912009-06-01114182510.15825/1995-1191-2009-4-18-25206VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTIONA. V. Vatazin0I. A. Vasilenko1A. L. Valov2V. B. Metelin3E. E. Kruglov4A. Ya. Tsalman5M.F. Vladimirsky Moscow Regional Research Clinical Institute, MoscowRussian Research Clinical Centre of Gerontology, MoscowRussian Children Clinical Hospital, MoscowRussian Research Clinical Centre of Gerontology, MoscowM.F. Vladimirsky Moscow Regional Research Clinical Institute, MoscowM.F. Vladimirsky Moscow Regional Research Clinical Institute, MoscowThe article focuses on the results of the investigation of peripheral blood lymphocyte morphofunctional status in healthy volunteers and renal allograft recipients for early postoperative period. Working out noninvasive tests for diagnosis of acute renal allograft rejection based on the measuring of cell morphometric parameters by method of coherent phase microscopy (CPM). It was found out that the lymphocyte phase height was proportional cell image density and its geometrical thickness. Our results showed that the variations of immunocompetent cell morphometric indicants can be in advance the dynamics of blood creatine increasing and answer for early criteria of acute renal allograft rejection.https://journal.transpl.ru/vtio/article/view/263renal transplantationacute allograft rejectionlymphocytesmorphometry
collection DOAJ
language Russian
format Article
sources DOAJ
author A. V. Vatazin
I. A. Vasilenko
A. L. Valov
V. B. Metelin
E. E. Kruglov
A. Ya. Tsalman
spellingShingle A. V. Vatazin
I. A. Vasilenko
A. L. Valov
V. B. Metelin
E. E. Kruglov
A. Ya. Tsalman
VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
Vestnik Transplantologii i Iskusstvennyh Organov
renal transplantation
acute allograft rejection
lymphocytes
morphometry
author_facet A. V. Vatazin
I. A. Vasilenko
A. L. Valov
V. B. Metelin
E. E. Kruglov
A. Ya. Tsalman
author_sort A. V. Vatazin
title VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
title_short VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
title_full VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
title_fullStr VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
title_full_unstemmed VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
title_sort vital computer morphometry of limphocytes in diagnosis of acute renal allograft rejection
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
series Vestnik Transplantologii i Iskusstvennyh Organov
issn 1995-1191
publishDate 2009-06-01
description The article focuses on the results of the investigation of peripheral blood lymphocyte morphofunctional status in healthy volunteers and renal allograft recipients for early postoperative period. Working out noninvasive tests for diagnosis of acute renal allograft rejection based on the measuring of cell morphometric parameters by method of coherent phase microscopy (CPM). It was found out that the lymphocyte phase height was proportional cell image density and its geometrical thickness. Our results showed that the variations of immunocompetent cell morphometric indicants can be in advance the dynamics of blood creatine increasing and answer for early criteria of acute renal allograft rejection.
topic renal transplantation
acute allograft rejection
lymphocytes
morphometry
url https://journal.transpl.ru/vtio/article/view/263
work_keys_str_mv AT avvatazin vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
AT iavasilenko vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
AT alvalov vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
AT vbmetelin vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
AT eekruglov vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
AT ayatsalman vitalcomputermorphometryoflimphocytesindiagnosisofacuterenalallograftrejection
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