Comparative secretome analysis of rat stomach under different nutritional status
The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteo...
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doaj-25ded1981eda41c2899ac89e1bdc14782020-11-24T21:43:31ZengElsevierData in Brief2352-34092015-06-013C626610.1016/j.dib.2015.01.002Comparative secretome analysis of rat stomach under different nutritional statusLucia L. Senin0Arturo Roca-Rivada1Cecilia Castelao2Jana Alonso3Cintia Folgueira4Felipe F. Casanueva5Maria Pardo6Luisa M. Seoane7Grupo Fisiopatologia Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, SpainCIBER Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto de Salud Carlos III, Santiago de Compostela, SpainGrupo Fisiopatologia Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, SpainLaboratorio de Proteómica, Instituto de Investigación Sanitaria de Santiago de Compostela (CHUS/SERGAS), SpainGrupo Fisiopatologia Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, SpainCIBER Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto de Salud Carlos III, Santiago de Compostela, SpainCIBER Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto de Salud Carlos III, Santiago de Compostela, SpainGrupo Fisiopatologia Endocrina, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, SpainThe fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteomic analysis of gastric secretome was performed. To validate this gastric explant system for proteomic analysis, the identification of ghrelin, a classical gastric derived peptide, was performed by MS. In addition, the differential analysis of gastric secretomes under differential nutritional status (control feeding vs fasting vs re-feeding) was performed. The MS identified proteins are showed in the present manuscript. The data supplied in this article is related to the research article entitled “Comparative secretome analysis of rat stomach under different nutritional status” [1].http://www.sciencedirect.com/science/article/pii/S2352340915000049 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lucia L. Senin Arturo Roca-Rivada Cecilia Castelao Jana Alonso Cintia Folgueira Felipe F. Casanueva Maria Pardo Luisa M. Seoane |
spellingShingle |
Lucia L. Senin Arturo Roca-Rivada Cecilia Castelao Jana Alonso Cintia Folgueira Felipe F. Casanueva Maria Pardo Luisa M. Seoane Comparative secretome analysis of rat stomach under different nutritional status Data in Brief |
author_facet |
Lucia L. Senin Arturo Roca-Rivada Cecilia Castelao Jana Alonso Cintia Folgueira Felipe F. Casanueva Maria Pardo Luisa M. Seoane |
author_sort |
Lucia L. Senin |
title |
Comparative secretome analysis of rat stomach under different nutritional status |
title_short |
Comparative secretome analysis of rat stomach under different nutritional status |
title_full |
Comparative secretome analysis of rat stomach under different nutritional status |
title_fullStr |
Comparative secretome analysis of rat stomach under different nutritional status |
title_full_unstemmed |
Comparative secretome analysis of rat stomach under different nutritional status |
title_sort |
comparative secretome analysis of rat stomach under different nutritional status |
publisher |
Elsevier |
series |
Data in Brief |
issn |
2352-3409 |
publishDate |
2015-06-01 |
description |
The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteomic analysis of gastric secretome was performed. To validate this gastric explant system for proteomic analysis, the identification of ghrelin, a classical gastric derived peptide, was performed by MS. In addition, the differential analysis of gastric secretomes under differential nutritional status (control feeding vs fasting vs re-feeding) was performed. The MS identified proteins are showed in the present manuscript. The data supplied in this article is related to the research article entitled “Comparative secretome analysis of rat stomach under different nutritional status” [1]. |
url |
http://www.sciencedirect.com/science/article/pii/S2352340915000049 |
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