Effect of High-Dose VS Standard-Dose Vitamin D<sub>3</sub> Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial

Effect of High-Dose VS Standard-Dose Vitamin D<sub>3</sub> Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial

Skeletal muscle and adipose tissue express the vitamin D receptor and may be a mechanism through which vitamin D supplementation slows cancer progression and reduces cancer death. In this exploratory analysis of a double-blind, multicenter, randomized phase II clinical trial, 105 patients with advan...

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Bibliographic Details
Main Authors: Justin C. Brown, Michael H. Rosenthal, Chao Ma, Sui Zhang, Halla S. Nimeiri, Nadine J. McCleary, Thomas A. Abrams, Matthew B. Yurgelun, James M. Cleary, Douglas A. Rubinson, Deborah Schrag, Andrea J. Bullock, Jill Allen, Dan Zuckerman, Emily Chan, Jennifer A. Chan, Brian Wolpin, Michael Constantine, Douglas J. Weckstein, Meredith A. Faggen, Christian A. Thomas, Chryssanthi Kournioti, Chen Yuan, Hui Zheng, Bruce W. Hollis, Charles S. Fuchs, Kimmie Ng, Jeffrey A. Meyerhardt
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
adipose tissue
colorectal neoplasms
cholecalciferol
mediation
prognosis
randomized
Online Access:https://www.mdpi.com/2072-6694/12/11/3451

Internet

https://www.mdpi.com/2072-6694/12/11/3451

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