Application progress of temozolomide in clinical tumor chemotherapy
<p>Temozolomide is an imidazotetrazine derivative of the alkylating agent, which is used to treat central nervous system tumors, especially malignant brain gliomas. It is a milestone in brain giloma chemotherapy. Recently, some researchers used temozolomide for the treatment of other tumors, i...
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doaj-25f4d517bf3e4d50a37bfbc68cf489782020-11-24T22:23:43ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312013-12-01131210441048866Application progress of temozolomide in clinical tumor chemotherapyCheng ZHONG0Bin WANG1Sheng-qing LV2Department of Neurosurgery, Yongchuan People's Hospital, Chongqing 401000, ChinaDepartment of Neurosurgery, Yongchuan People's Hospital, Chongqing 401000, ChinaDepartment of Neurosurgery, Xinqiao Hospital, the Third Military Medical University of Chinese PLA, Chongqing 400037, China<p>Temozolomide is an imidazotetrazine derivative of the alkylating agent, which is used to treat central nervous system tumors, especially malignant brain gliomas. It is a milestone in brain giloma chemotherapy. Recently, some researchers used temozolomide for the treatment of other tumors, including melanoma, intracranial metastatic tumors, lymphomas, refractory leukaemia, pituitary tumors, lung cancer, and so on. Some results are encouraging in clinical trials. Here, this paper makes a review on the antineoplastic mechanisms of temozolomide, its indications in gliomas and some unusual indications.</p><p> </p><p>doi:10.3969/j.issn.1672-6731.2013.12.013</p>http://www.cjcnn.org/index.php/cjcnn/article/view/867GliomaTemozolomide (not in MeSH)Review |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cheng ZHONG Bin WANG Sheng-qing LV |
spellingShingle |
Cheng ZHONG Bin WANG Sheng-qing LV Application progress of temozolomide in clinical tumor chemotherapy Chinese Journal of Contemporary Neurology and Neurosurgery Glioma Temozolomide (not in MeSH) Review |
author_facet |
Cheng ZHONG Bin WANG Sheng-qing LV |
author_sort |
Cheng ZHONG |
title |
Application progress of temozolomide in clinical tumor chemotherapy |
title_short |
Application progress of temozolomide in clinical tumor chemotherapy |
title_full |
Application progress of temozolomide in clinical tumor chemotherapy |
title_fullStr |
Application progress of temozolomide in clinical tumor chemotherapy |
title_full_unstemmed |
Application progress of temozolomide in clinical tumor chemotherapy |
title_sort |
application progress of temozolomide in clinical tumor chemotherapy |
publisher |
Tianjin Huanhu Hospital |
series |
Chinese Journal of Contemporary Neurology and Neurosurgery |
issn |
1672-6731 |
publishDate |
2013-12-01 |
description |
<p>Temozolomide is an imidazotetrazine derivative of the alkylating agent, which is used to treat central nervous system tumors, especially malignant brain gliomas. It is a milestone in brain giloma chemotherapy. Recently, some researchers used temozolomide for the treatment of other tumors, including melanoma, intracranial metastatic tumors, lymphomas, refractory leukaemia, pituitary tumors, lung cancer, and so on. Some results are encouraging in clinical trials. Here, this paper makes a review on the antineoplastic mechanisms of temozolomide, its indications in gliomas and some unusual indications.</p><p> </p><p>doi:10.3969/j.issn.1672-6731.2013.12.013</p> |
topic |
Glioma Temozolomide (not in MeSH) Review |
url |
http://www.cjcnn.org/index.php/cjcnn/article/view/867 |
work_keys_str_mv |
AT chengzhong applicationprogressoftemozolomideinclinicaltumorchemotherapy AT binwang applicationprogressoftemozolomideinclinicaltumorchemotherapy AT shengqinglv applicationprogressoftemozolomideinclinicaltumorchemotherapy |
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1725764128218284032 |