Toxic effect of silicone oil on optic nerve

Silicone oil has been used as a safe and effective long-term vitreous substitute(VS)for more than 50 years. Clinically, it is currently widely used in surgical patients with severe ocular trauma and various complex vitreoretinal diseases, which has improved the prognosis of some previously incurable...

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Bibliographic Details
Main Authors: Jing Xu, Fang Wang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-05-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2019/5/201905018.pdf
Description
Summary:Silicone oil has been used as a safe and effective long-term vitreous substitute(VS)for more than 50 years. Clinically, it is currently widely used in surgical patients with severe ocular trauma and various complex vitreoretinal diseases, which has improved the prognosis of some previously incurable eye diseases. A series of toxic effects caused by the long-term retention of silicone oil in the vitreous cavity have attracted great attention. Based on the physicochemical properties of silicone oil, this review will analyze and summarize the toxic effects of silicone oil on the optic nerve, as well as its mechanism.
ISSN:1672-5123
1672-5123