Global Stabilization of Boolean Networks to Control the Heterogeneity of Cellular Responses
Boolean networks (BNs) have been widely used as a useful model for molecular regulatory networks in systems biology. In the state space of BNs, attractors represent particular cell phenotypes. For targeted therapy of cancer, there is a pressing need to control the heterogeneity of cellular responses...
Main Authors: | Jung-Min Yang, Chun-Kyung Lee, Kwang-Hyun Cho |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-07-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2018.00774/full |
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