Balsalazide Potentiates Parthenolide-Mediated Inhibition of Nuclear Factor-κB Signaling in HCT116 Human Colorectal Cancer Cells

Balsalazide Potentiates Parthenolide-Mediated Inhibition of Nuclear Factor-κB Signaling in HCT116 Human Colorectal Cancer Cells

Background/AimsBalsalazide is an anti-inflammatory drug used in the treatment of inflammatory bowel disease. Balsalazide can reduce inflammatory responses via several mechanisms, including inhibition of nuclear factor-κB (NF-κB) activity. Parthenolide (PT) inhibits NF-κB and exerts promising antican...

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Bibliographic Details
Main Authors: Hyun-Young Kim, Se-Lim Kim, Young-Ran Park, Yu-Chuan Liu, Seung Young Seo, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Sang Wook Kim
Format: Article
Language:English
Published: Korean Association for the Study of Intestinal Diseases 2015-07-01
Series:Intestinal Research
Subjects:
Balsalazide
Parthenolide
NF-κB
Apoptosis
Colorectal neoplasms
Online Access:http://www.irjournal.org/upload/pdf/ir-13-233.pdf

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