Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche.
For females, menarche is a most significant physiological event. Age at menarche (AAM) is a trait with high genetic determination and is associated with major complex diseases in women. However, specific genes for AAM variation are largely unknown. To identify genetic factors underlying AAM variatio...
Main Authors: | Yao-Zhong Liu, Yan-Fang Guo, Liang Wang, Li-Jun Tan, Xiao-Gang Liu, Yu-Fang Pei, Han Yan, Dong-Hai Xiong, Fei-Yan Deng, Na Yu, Yin-Ping Zhang, Lei Zhang, Shu-Feng Lei, Xiang-Ding Chen, Hong-Bin Liu, Xue-Zhen Zhu, Shawn Levy, Christopher J Papasian, Betty M Drees, James J Hamilton, Robert R Recker, Hong-Wen Deng |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2652107?pdf=render |
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