Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling.
POU transcription factor Pou5f1 (Oct3/4) is required to maintain ES cells in an undifferentiated state. Here we show that global expression profiling of Oct3/4-manipulated ES cells delineates the downstream target genes of Oct3/4. Combined with data from genome-wide chromatin-immunoprecipitation (Ch...
Main Authors: | Ryo Matoba, Hitoshi Niwa, Shinji Masui, Satoshi Ohtsuka, Mark G Carter, Alexei A Sharov, Minoru S H Ko |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1762406?pdf=render |
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