Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not...
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MDPI AG
2012-03-01
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| Series: | Insects |
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| Online Access: | http://www.mdpi.com/2075-4450/3/1/324/ |
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doaj-265a47e64b4b4a489b8cf0e0b1f31c3f2020-11-24T23:09:04ZengMDPI AGInsects2075-44502012-03-013132433810.3390/insects3010324Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor ProteinsEdward B. DubrovskyTravis J. BernardoJuvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH.http://www.mdpi.com/2075-4450/3/1/324/Drosophila melanogasterjuvenile hormonenuclear receptorbHLH-PASmethoprene-tolerantgerm cell-expressed |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Edward B. Dubrovsky Travis J. Bernardo |
| spellingShingle |
Edward B. Dubrovsky Travis J. Bernardo Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins Insects Drosophila melanogaster juvenile hormone nuclear receptor bHLH-PAS methoprene-tolerant germ cell-expressed |
| author_facet |
Edward B. Dubrovsky Travis J. Bernardo |
| author_sort |
Edward B. Dubrovsky |
| title |
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins |
| title_short |
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins |
| title_full |
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins |
| title_fullStr |
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins |
| title_full_unstemmed |
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins |
| title_sort |
molecular mechanisms of transcription activation by juvenile hormone: a critical role for bhlh-pas and nuclear receptor proteins |
| publisher |
MDPI AG |
| series |
Insects |
| issn |
2075-4450 |
| publishDate |
2012-03-01 |
| description |
Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH. |
| topic |
Drosophila melanogaster juvenile hormone nuclear receptor bHLH-PAS methoprene-tolerant germ cell-expressed |
| url |
http://www.mdpi.com/2075-4450/3/1/324/ |
| work_keys_str_mv |
AT edwardbdubrovsky molecularmechanismsoftranscriptionactivationbyjuvenilehormoneacriticalroleforbhlhpasandnuclearreceptorproteins AT travisjbernardo molecularmechanismsoftranscriptionactivationbyjuvenilehormoneacriticalroleforbhlhpasandnuclearreceptorproteins |
| _version_ |
1725611711834095616 |