Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei.

Base J, β-D-glucosyl-hydroxymethyluracil, is a chromatin modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. In Trypanosoma brucei, J is enriched, along with histone H3 variant (H3.V), at sites involved in RNA Polymerase (RNAP) II termination and telomeric...

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Bibliographic Details
Main Authors: David Reynolds, Brigitte T Hofmeister, Laura Cliffe, Magdy Alabady, T Nicolai Siegel, Robert J Schmitz, Robert Sabatini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4721609?pdf=render

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