Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei.
Base J, β-D-glucosyl-hydroxymethyluracil, is a chromatin modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. In Trypanosoma brucei, J is enriched, along with histone H3 variant (H3.V), at sites involved in RNA Polymerase (RNAP) II termination and telomeric...
Main Authors: | David Reynolds, Brigitte T Hofmeister, Laura Cliffe, Magdy Alabady, T Nicolai Siegel, Robert J Schmitz, Robert Sabatini |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4721609?pdf=render |
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