In Vivo Visualization of Active Polysynaptic Circuits With Longitudinal Manganese-Enhanced MRI (MEMRI)

In Vivo Visualization of Active Polysynaptic Circuits With Longitudinal Manganese-Enhanced MRI (MEMRI)

Manganese-enhanced magnetic resonance imaging (MEMRI) is a powerful tool for in vivo non-invasive whole-brain mapping of neuronal activity. Mn2+ enters active neurons via voltage-gated calcium channels and increases local contrast in T1-weighted images. Given the property of Mn2+ of axonal transport...

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Bibliographic Details
Main Authors: Suellen Almeida-Corrêa, Michael Czisch, Carsten T. Wotjak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neural Circuits
Subjects:
manganese-enhanced MRI
neuroimaging
brain connectomics
Mn2+ transport
barrel-cortex
whiskers
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2018.00042/full

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