The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling Pathway

The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling Pathway

Sonneratia apetala Buch-Ham., an exotic mangrove species with antidiabetic, antibacterial, and antioxidant capacities, mainly distributes in the southeast coastal areas in China. The present work investigated the protective effects of Sonneratia apetala leaves and branches extraction (SAL) on hyperu...

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Bibliographic Details
Main Authors: Yu-Lin Wu, Jin-Fen Chen, Lin-Yun Jiang, Xiao-Li Wu, Yu-Hong Liu, Chang-Jun Gao, Yan Wu, Xiao-Qing Yi, Zi-Ren Su, Jian Cai, Jian-Nan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
Sonneratia apetala leaves and branches
hyperuricemia
renal uric acid transporters
oxidative stress
JAK/STAT pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.698219/full

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