Systems genetic validation of the SNP-metabolite association in rice via metabolite-pathway-based phenome-wide association scans

Systems genetic validation of the SNP-metabolite association in rice via metabolite-pathway-based phenome-wide association scans

In the post-GWAS (Genome-Wide Association Scan) era, the interpretation of GWAS results is crucial to screen for highly relevant phenotype-genotype association pairs. Based on the single genotype-phenotype association test and a pathway enrichment analysis, we propose a Metabolite-pathway-based Phen...

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Bibliographic Details
Main Authors: Yaping eLu, Yemao eLiu, Xiaohui eNiu, Qingyong eYang, Xuehai eHu, Hong-Yu eZhang, Jingbo eXia
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Plant Science
Subjects:
replication
metabolite
Wilcoxon rank-sum test
Association scan
upper tier metabolite pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01027/full

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