Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics
Background: Diabetes affects approximately 250 million people in the world. Cardiovascular autonomic neuropathy is a common complication of diabetes that leads to severe postural hypotension, exercise intolerance, and increased incidence of silent myocardial infarction. Objective: To determine the v...
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Sociedade Brasileira de Cardiologia (SBC)
2015-01-01
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doaj-26ebd2c804f44ac88c030c43bb862ff42020-11-24T22:44:25ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702015-01-0100010.5935/abc.20150073S0066-782X2015005050073Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed DiabeticsAnaclara Michel-ChávezBruno EstañolJosé Antonio Gien-LópezAdriana Robles-CabreraMaría Elena Huitrado-DuarteRené Moreno-MoralesBrayans Becerra-LunaBackground: Diabetes affects approximately 250 million people in the world. Cardiovascular autonomic neuropathy is a common complication of diabetes that leads to severe postural hypotension, exercise intolerance, and increased incidence of silent myocardial infarction. Objective: To determine the variability of heart rate (HR) and systolic blood pressure (SBP) in recently diagnosed diabetic patients. Methods: The study included 30 patients with a diagnosis of type 2 diabetes of less than 2 years and 30 healthy controls. We used a Finapres® device to measure during five minutes beat-to-beat HR and blood pressure in three experimental conditions: supine position, standing position, and rhythmic breathing at 0.1 Hz. The results were analyzed in the time and frequency domains. Results: In the HR analysis, statistically significant differences were found in the time domain, specifically on short-term values such as standard deviation of NN intervals (SDNN), root mean square of successive differences (RMSSD), and number of pairs of successive NNs that differ by more than 50 ms (pNN50). In the BP analysis, there were no significant differences, but there was a sympathetic dominance in all three conditions. The baroreflex sensitivity (BRS) decreased in patients with early diabetes compared with healthy subjects during the standing maneuver. Conclusions: There is a decrease in HR variability in patients with early type 2 diabetes. No changes were observed in the BP analysis in the supine position, but there were changes in BRS with the standing maneuver, probably due to sympathetic hyperactivity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015005050073&lng=en&tlng=enFrequência CardíacaPressão ArterialDiabetes Mellitus / diagnósticoComplicações do DiabetesNeuropatias Diabéticas |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anaclara Michel-Chávez Bruno Estañol José Antonio Gien-López Adriana Robles-Cabrera María Elena Huitrado-Duarte René Moreno-Morales Brayans Becerra-Luna |
spellingShingle |
Anaclara Michel-Chávez Bruno Estañol José Antonio Gien-López Adriana Robles-Cabrera María Elena Huitrado-Duarte René Moreno-Morales Brayans Becerra-Luna Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics Arquivos Brasileiros de Cardiologia Frequência Cardíaca Pressão Arterial Diabetes Mellitus / diagnóstico Complicações do Diabetes Neuropatias Diabéticas |
author_facet |
Anaclara Michel-Chávez Bruno Estañol José Antonio Gien-López Adriana Robles-Cabrera María Elena Huitrado-Duarte René Moreno-Morales Brayans Becerra-Luna |
author_sort |
Anaclara Michel-Chávez |
title |
Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics |
title_short |
Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics |
title_full |
Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics |
title_fullStr |
Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics |
title_full_unstemmed |
Heart Rate and Systolic Blood Pressure Variability on Recently Diagnosed Diabetics |
title_sort |
heart rate and systolic blood pressure variability on recently diagnosed diabetics |
publisher |
Sociedade Brasileira de Cardiologia (SBC) |
series |
Arquivos Brasileiros de Cardiologia |
issn |
1678-4170 |
publishDate |
2015-01-01 |
description |
Background: Diabetes affects approximately 250 million people in the world. Cardiovascular autonomic neuropathy is a common complication of diabetes that leads to severe postural hypotension, exercise intolerance, and increased incidence of silent myocardial infarction. Objective: To determine the variability of heart rate (HR) and systolic blood pressure (SBP) in recently diagnosed diabetic patients. Methods: The study included 30 patients with a diagnosis of type 2 diabetes of less than 2 years and 30 healthy controls. We used a Finapres® device to measure during five minutes beat-to-beat HR and blood pressure in three experimental conditions: supine position, standing position, and rhythmic breathing at 0.1 Hz. The results were analyzed in the time and frequency domains. Results: In the HR analysis, statistically significant differences were found in the time domain, specifically on short-term values such as standard deviation of NN intervals (SDNN), root mean square of successive differences (RMSSD), and number of pairs of successive NNs that differ by more than 50 ms (pNN50). In the BP analysis, there were no significant differences, but there was a sympathetic dominance in all three conditions. The baroreflex sensitivity (BRS) decreased in patients with early diabetes compared with healthy subjects during the standing maneuver. Conclusions: There is a decrease in HR variability in patients with early type 2 diabetes. No changes were observed in the BP analysis in the supine position, but there were changes in BRS with the standing maneuver, probably due to sympathetic hyperactivity. |
topic |
Frequência Cardíaca Pressão Arterial Diabetes Mellitus / diagnóstico Complicações do Diabetes Neuropatias Diabéticas |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015005050073&lng=en&tlng=en |
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