Sensitization by subcutaneous route is superior to intraperitoneal route in induction of asthma by house dust mite in a murine mode

ABSTRACT Objective To develop a new experimental model of chronic allergic pulmonary disease induced by house dust mite, with marked production of specific immunoglobulin E (IgE), eosinophilic inflammatory infiltrate in the airways and remodeling, comparing two different routes of sensitization....

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Main Authors: Marcelo Vivolo Aun, Beatriz Mangueira Saraiva-Romanholo, Francine Maria de Almeida, Thayse Regina Brüggemann, Jorge Kalil, Milton de Arruda Martins, Fernanda Magalhães Arantes-Costa, Pedro Giavina-Bianchi
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein
Series:Einstein (São Paulo)
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000400560&lng=en&tlng=en