Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro

Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Brazilian isolates presented, beside the classical structured den...

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Main Authors: Ortrud Monika Barth, Luzia Monteiro de Castro Côrtes, Elisabeth Lampe, José da Costa Farias Filho
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1994-03-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000100004
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spelling doaj-276a9505e344440c97c0326250dbf1da2020-11-24T23:08:27ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80601994-03-01891212410.1590/S0074-02761994000100004Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de JaneiroOrtrud Monika BarthLuzia Monteiro de Castro CôrtesElisabeth LampeJosé da Costa Farias FilhoDengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Brazilian isolates presented, beside the classical structured dengue virus particles, fuzzy coated virus-like particles, never observed in thereferencial New Guinea C virus strain. more numerous DEN-2 virus particles, fuzzy coated virus-like particles, defective virus particles and smooth membrane structures inside the rough endoplasmic reticulum characterized the unique fatal isolate examined.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000100004flaviviridaedengue-2virus replicationultrastructure
collection DOAJ
language English
format Article
sources DOAJ
author Ortrud Monika Barth
Luzia Monteiro de Castro Côrtes
Elisabeth Lampe
José da Costa Farias Filho
spellingShingle Ortrud Monika Barth
Luzia Monteiro de Castro Côrtes
Elisabeth Lampe
José da Costa Farias Filho
Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
Memórias do Instituto Oswaldo Cruz.
flaviviridae
dengue-2
virus replication
ultrastructure
author_facet Ortrud Monika Barth
Luzia Monteiro de Castro Côrtes
Elisabeth Lampe
José da Costa Farias Filho
author_sort Ortrud Monika Barth
title Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
title_short Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
title_full Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
title_fullStr Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
title_full_unstemmed Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
title_sort ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in rio de janeiro
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 0074-0276
1678-8060
publishDate 1994-03-01
description Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Brazilian isolates presented, beside the classical structured dengue virus particles, fuzzy coated virus-like particles, never observed in thereferencial New Guinea C virus strain. more numerous DEN-2 virus particles, fuzzy coated virus-like particles, defective virus particles and smooth membrane structures inside the rough endoplasmic reticulum characterized the unique fatal isolate examined.
topic flaviviridae
dengue-2
virus replication
ultrastructure
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000100004
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AT elisabethlampe ultrastructuralaspectsofvirusreplicationinonefatalcaseandseveralotherisolatesfromadenguetype2outbreakinriodejaneiro
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