The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran
Introduction: Ovarian cancer is the second most common malignancy in women, the most common cause of gynecologic cancer deaths, and most patients have advanced stage disease at the time of diagnosis. The purpose of this study was to estimate the 5-year survival of patients with epithelial ovarian...
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doaj-2771c58987f64c5181c46e3f599499b42020-11-24T20:57:17ZengElectronic PhysicianElectronic Physician2008-58422008-58422015-10-01761399140610.14661/1399The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, IranMojgan Karimi-ZarchiSeyed Mohammad Reza MortazavizadehNasrollah BashardustNeda ZakerianMahbube ZaidabadiPouria Yazdian-AnariSoraya TeimooriIntroduction: Ovarian cancer is the second most common malignancy in women, the most common cause of gynecologic cancer deaths, and most patients have advanced stage disease at the time of diagnosis. The purpose of this study was to estimate the 5-year survival of patients with epithelial ovarian cancer based on age, tumor histology, stage of disease, and type of treatment. Methods: This study was conducted on 120 patients with epithelial ovarian cancer referred to Shahid Sadoughi hospital and Shah Vali oncology clinic of Yazd from 2006 to 2012. Demographic data and patient records were studied to evaluate the treatment outcome, pathology of the tumor, and stage of disease. Finally, the overall survival rate and tumor-free survival of patients was assessed. Results: The mean patient age was 53.87± 14.11 years. Most participants had stage I (36.7%) or stage II (35%) disease. Serous adenocarcinoma (57.6%) was the most common pathology found in patients with epithelial ovarian cancer. The overall survival of patients in this study was significantly associated with the histological tumor type (p = 0.000) and disease stage (p = 0.0377). Stage I (84.18%) and serous adenocarcinoma (72.81%) demonstrated the best survival. The tumor-free survival rates were not associated with histology types (p = 0.079), surgical procedure (p = 0.18), or chemotherapy (p = 0.18). Conclusion: The survival of patients with epithelial ovarian cancer was significantly associated with disease stage. Serous adenocarcinoma also had the best prognosis among the pathologies studied. Therefore, early detection of ovarian cancer can substantially increase the survival rate.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623803/Epithelial ovarian cancerepidemiologic pointssurvival rate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mojgan Karimi-Zarchi Seyed Mohammad Reza Mortazavizadeh Nasrollah Bashardust Neda Zakerian Mahbube Zaidabadi Pouria Yazdian-Anari Soraya Teimoori |
spellingShingle |
Mojgan Karimi-Zarchi Seyed Mohammad Reza Mortazavizadeh Nasrollah Bashardust Neda Zakerian Mahbube Zaidabadi Pouria Yazdian-Anari Soraya Teimoori The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran Electronic Physician Epithelial ovarian cancer epidemiologic points survival rate |
author_facet |
Mojgan Karimi-Zarchi Seyed Mohammad Reza Mortazavizadeh Nasrollah Bashardust Neda Zakerian Mahbube Zaidabadi Pouria Yazdian-Anari Soraya Teimoori |
author_sort |
Mojgan Karimi-Zarchi |
title |
The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran |
title_short |
The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran |
title_full |
The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran |
title_fullStr |
The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran |
title_full_unstemmed |
The Clinicopathologic Characteristics and 5-year Survival Rate of Epithelial Ovarian Cancer in Yazd, Iran |
title_sort |
clinicopathologic characteristics and 5-year survival rate of epithelial ovarian cancer in yazd, iran |
publisher |
Electronic Physician |
series |
Electronic Physician |
issn |
2008-5842 2008-5842 |
publishDate |
2015-10-01 |
description |
Introduction: Ovarian cancer is the second most common malignancy in women, the most common cause of
gynecologic cancer deaths, and most patients have advanced stage disease at the time of diagnosis. The purpose
of this study was to estimate the 5-year survival of patients with epithelial ovarian cancer based on age, tumor
histology, stage of disease, and type of treatment.
Methods: This study was conducted on 120 patients with epithelial ovarian cancer referred to Shahid Sadoughi
hospital and Shah Vali oncology clinic of Yazd from 2006 to 2012. Demographic data and patient records were
studied to evaluate the treatment outcome, pathology of the tumor, and stage of disease. Finally, the overall
survival rate and tumor-free survival of patients was assessed.
Results: The mean patient age was 53.87± 14.11 years. Most participants had stage I (36.7%) or stage II (35%)
disease. Serous adenocarcinoma (57.6%) was the most common pathology found in patients with epithelial
ovarian cancer. The overall survival of patients in this study was significantly associated with the histological
tumor type (p = 0.000) and disease stage (p = 0.0377). Stage I (84.18%) and serous adenocarcinoma (72.81%)
demonstrated the best survival. The tumor-free survival rates were not associated with histology types (p =
0.079), surgical procedure (p = 0.18), or chemotherapy (p = 0.18).
Conclusion: The survival of patients with epithelial ovarian cancer was significantly associated with disease
stage. Serous adenocarcinoma also had the best prognosis among the pathologies studied. Therefore, early
detection of ovarian cancer can substantially increase the survival rate. |
topic |
Epithelial ovarian cancer epidemiologic points survival rate |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623803/ |
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