Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry
A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-source decay (MALDI-ISD) to investigate heter...
Main Authors: | Bao Quoc Tran, Christopher Barton, Jinhua Feng, Aimee Sandjong, Sung Hwan Yoon, Shivangi Awasthi, Tao Liang, Mohd M. Khan, David P.A. Kilgour, David R. Goodlett, Young Ah Goo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Data in Brief |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340915003261 |
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