Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia
Health care personnel at a community hospital have used cinnamon stomachic mixture for treatment of patients with functional dyspepsia for many years and they claimed that cinnamon stomachic mixture was effective without any supportive evidence. Objective: To determine the efficacy, safety, patient...
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Mahidol University
2006-11-01
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Online Access: | https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246001 |
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doaj-27c31131c77147448bb226e53869d7f02021-08-13T10:01:02ZengMahidol UniversitySiriraj Medical Journal2228-80822006-11-015811Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional DyspepsiaSunanta Jindarat0Chaweewan Muangnoi1Dalicha Changsiriporn2Anuchit Platong3Bangon Thanamontra4Duangrat Chiewchanwit5Viparat Vongvanvatana6Noppawan Rongrungsri7Kumrai Krittasilp8 Nutteera Kaewkong9Sairung Kantawan10Nilnetr Virasombat11Veena Mongkolporn12Wilai Prakobkij13Khanidtha Wanleepong14Chatchawal Maneekul15Sittikom Benchakhanta16Piyamit Boonpok17Wilaiwan Kunnasut18Laddawan Tongkleaw19 Adisorn Vatthanasak20Jiranya Mookkhan21Chaiwat Jatuporn22Kullana Tuntiprawan23Sirirung Teerawongseree24Saowakhon Ussawasrisuwan25 Pojawan Thamcharoen26Thunyaporn Keawsontaya27Anchalee Chuthaputti28Porntip Termviset29Visanu Thamlikitkul30U-thong HospitalU-thong HospitalU-thong HospitalU-thong HospitalU-thong HospitalU-thong HospitalBangkrathum HospitalBangkrathum HospitalBangkrathum HospitalBangkrathum HospitalBangkrathum HospitalSoongneon HospitalSoongneon HospitalSoongneon HospitalSoongneon HospitalSoongneon HospitalThe Crown Prince Hospital of LoengnokthaThe Crown Prince Hospital of LoengnokthaThe Crown Prince Hospital of LoengnokthaThe Crown Prince Hospital of LoengnokthaKudchum HospitalKudchum HospitalWangchan HospitalWangchan HospitalWangchan HospitalWangchan HospitalWangchan HospitalWangchan HospitalDepartment for Development of Thai Traditional and Alternative Medicine, Ministry of Public HealthDepartment for Development of Thai Traditional and Alternative Medicine, Ministry of Public HealthFaculty of Medicine Siriraj Hospital, Mahidol University Health care personnel at a community hospital have used cinnamon stomachic mixture for treatment of patients with functional dyspepsia for many years and they claimed that cinnamon stomachic mixture was effective without any supportive evidence. Objective: To determine the efficacy, safety, patients’ compliance and satisfaction with the treatment of cinnamon stomachic mixture. Methods: This was a randomized controlled study in 318 adults with functional dyspepsia presenting to 6 community hospitals. The patients were randomized to receive 105 mg of simethicone three times a day or 30 ml of cinnamon stomachic mixture three times a day for 7 to 14 days. The patients were evaluated for improvement of symptoms, compliance to medication and patients’ satisfaction with the treatment. The data were analysed by descriptive statistics, chi-square statistics, student t test, analysis of variance and non-parametric tests where appropriate. Results: One hundred and fifty patients received simethicone and 168 patients received cinnamon stomachic mixture. The baseline characteristics of the patients in both groups were not significantly different. The patients’ compliance to simethicone and cinnamon stomachic mixture was 82% and 89.3% respectively (p=0.09). The severity of the symptoms after treatment and the response rates were not significantly different between both groups. Side effects were observed in 9.3% and 9.5% in the simethicone group and the cinnamon stomachic mixture group respectively. Most of the patients in both groups were satisfied with the treatments they received. The cost of a 14-day course of cinnamon stomachic mixture was 36 baht compared with 84 baht for that of simethicone. Conclusion: Cinnamon stomachic mixture is effective and safe for the treatment of the patients with functional dyspepsia similar to simethicone. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246001Cinnamon stomachic mixturefunctional dyspepsiasimethicone |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sunanta Jindarat Chaweewan Muangnoi Dalicha Changsiriporn Anuchit Platong Bangon Thanamontra Duangrat Chiewchanwit Viparat Vongvanvatana Noppawan Rongrungsri Kumrai Krittasilp Nutteera Kaewkong Sairung Kantawan Nilnetr Virasombat Veena Mongkolporn Wilai Prakobkij Khanidtha Wanleepong Chatchawal Maneekul Sittikom Benchakhanta Piyamit Boonpok Wilaiwan Kunnasut Laddawan Tongkleaw Adisorn Vatthanasak Jiranya Mookkhan Chaiwat Jatuporn Kullana Tuntiprawan Sirirung Teerawongseree Saowakhon Ussawasrisuwan Pojawan Thamcharoen Thunyaporn Keawsontaya Anchalee Chuthaputti Porntip Termviset Visanu Thamlikitkul |
spellingShingle |
Sunanta Jindarat Chaweewan Muangnoi Dalicha Changsiriporn Anuchit Platong Bangon Thanamontra Duangrat Chiewchanwit Viparat Vongvanvatana Noppawan Rongrungsri Kumrai Krittasilp Nutteera Kaewkong Sairung Kantawan Nilnetr Virasombat Veena Mongkolporn Wilai Prakobkij Khanidtha Wanleepong Chatchawal Maneekul Sittikom Benchakhanta Piyamit Boonpok Wilaiwan Kunnasut Laddawan Tongkleaw Adisorn Vatthanasak Jiranya Mookkhan Chaiwat Jatuporn Kullana Tuntiprawan Sirirung Teerawongseree Saowakhon Ussawasrisuwan Pojawan Thamcharoen Thunyaporn Keawsontaya Anchalee Chuthaputti Porntip Termviset Visanu Thamlikitkul Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia Siriraj Medical Journal Cinnamon stomachic mixture functional dyspepsia simethicone |
author_facet |
Sunanta Jindarat Chaweewan Muangnoi Dalicha Changsiriporn Anuchit Platong Bangon Thanamontra Duangrat Chiewchanwit Viparat Vongvanvatana Noppawan Rongrungsri Kumrai Krittasilp Nutteera Kaewkong Sairung Kantawan Nilnetr Virasombat Veena Mongkolporn Wilai Prakobkij Khanidtha Wanleepong Chatchawal Maneekul Sittikom Benchakhanta Piyamit Boonpok Wilaiwan Kunnasut Laddawan Tongkleaw Adisorn Vatthanasak Jiranya Mookkhan Chaiwat Jatuporn Kullana Tuntiprawan Sirirung Teerawongseree Saowakhon Ussawasrisuwan Pojawan Thamcharoen Thunyaporn Keawsontaya Anchalee Chuthaputti Porntip Termviset Visanu Thamlikitkul |
author_sort |
Sunanta Jindarat |
title |
Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia |
title_short |
Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia |
title_full |
Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia |
title_fullStr |
Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia |
title_full_unstemmed |
Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia |
title_sort |
efficacy and safety of cinnamon stomachic mixture for patients with functional dyspepsia |
publisher |
Mahidol University |
series |
Siriraj Medical Journal |
issn |
2228-8082 |
publishDate |
2006-11-01 |
description |
Health care personnel at a community hospital have used cinnamon stomachic mixture for treatment of patients with functional dyspepsia for many years and they claimed that cinnamon stomachic mixture was effective without any supportive evidence.
Objective: To determine the efficacy, safety, patients’ compliance and satisfaction with the treatment of cinnamon stomachic mixture.
Methods: This was a randomized controlled study in 318 adults with functional dyspepsia presenting to 6 community hospitals. The patients were randomized to receive 105 mg of simethicone three times a day or 30 ml of cinnamon stomachic mixture three times a day for 7 to 14 days. The patients were evaluated for improvement of symptoms, compliance to medication and patients’ satisfaction with the treatment. The data were analysed by descriptive statistics, chi-square statistics, student t test, analysis of variance and non-parametric tests where appropriate.
Results: One hundred and fifty patients received simethicone and 168 patients received cinnamon stomachic mixture. The baseline characteristics of the patients in both groups were not significantly different. The patients’ compliance to simethicone and cinnamon stomachic mixture was 82% and 89.3% respectively (p=0.09). The severity of the symptoms after treatment and the response rates were not significantly different between both groups. Side effects were observed in 9.3% and 9.5% in the simethicone group and the cinnamon stomachic mixture group respectively. Most of the patients in both groups were satisfied with the treatments they received. The cost of a 14-day course of cinnamon stomachic mixture was 36 baht compared with 84 baht for that of simethicone.
Conclusion: Cinnamon stomachic mixture is effective and safe for the treatment of the patients with functional dyspepsia similar to simethicone.
|
topic |
Cinnamon stomachic mixture functional dyspepsia simethicone |
url |
https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246001 |
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