Lipopolysaccharide induces IFN-γ production in human NK cells

NK cells have been shown to play a regulatory role in sepsis. According to the current view, NK cells become activated via macrophages or dendritic cells primed by lipopolysaccharide (LPS). Recently TLR4 gene expression was detected in human NK cells suggesting the possibility of a direct action of...

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Bibliographic Details
Main Authors: Leonid M Kanevskiy, William G Telford, Alexander M Sapozhnikov, Elena I Kovalenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00011/full