Lipopolysaccharide induces IFN-γ production in human NK cells
NK cells have been shown to play a regulatory role in sepsis. According to the current view, NK cells become activated via macrophages or dendritic cells primed by lipopolysaccharide (LPS). Recently TLR4 gene expression was detected in human NK cells suggesting the possibility of a direct action of...
Main Authors: | Leonid M Kanevskiy, William G Telford, Alexander M Sapozhnikov, Elena I Kovalenko |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-01-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00011/full |
Similar Items
-
NK Cells: Uncertain Allies against Malaria
by: Asia-Sophia Wolf, et al.
Published: (2017-03-01) -
Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques
by: Diego A. Vargas-Inchaustegui, et al.
Published: (2016-08-01) -
Human NK Cell Up-regulation of CD69, HLA-DR, Interferon γ Secretion and Cytotoxic Activity by Plasmacytoid Dendritic Cells is Regulated through Overlapping but Different Pathways
by: Heather Donaghy, et al.
Published: (2009-01-01) -
Differential cytotoxicity but augmented IFN-γ secretion by NK cells after interaction with monocytes from humans, and those from wild type and myeloid specific COX-2 knockout mice
by: Han-Ching eTseng, et al.
Published: (2015-06-01) -
Human decidual NK cells: unique and tightly regulated effector functions in healthy and pathogen-infected pregnancies
by: Philippe eLe Bouteiller, et al.
Published: (2013-11-01)