Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronal cell death to seizure-induced neuronal injury

Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronal cell death to seizure-induced neuronal injury

Pilocarpine-induced status epilepticus (PCSE) is a widely used model to study neurodegeneration in limbic structures after prolonged epileptic seizures. However, mechanisms mediating neuronal cell death in this model require further characterization. Examining the expression time course and spatial...

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Bibliographic Details
Main Authors: Jens Weise, Tobias Engelhorn, Arnd Dörfler, Stefanie Aker, Mathias Bähr, Andreas Hufnagel
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
Subjects:
Status epilepticus
Pilocarpine
Caspase-3
Apoptosis
Neuronal cell death
Rats
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002608

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