A Zic2/Runx2/NOLC1 signaling axis mediates tumor growth and metastasis in clear cell renal cell carcinoma
Abstract Clear cell renal cell carcinoma (ccRCC) is one of the most common malignancies with rapid growth and high metastasis, but lacks effective therapeutic targets. Here, using public sequencing data analyses, quantitative real-time PCR assay, western blotting, and IHC staining, we characterized...
Main Authors: | Chen-Yan Wu, Lei Li, Shi-Lu Chen, Xia Yang, Chris Zhiyi Zhang, Yun Cao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03617-8 |
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