Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina
Background: High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. Objective: To assess the correlation between serum hs-CRP le...
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Sociedade Brasileira de Cardiologia (SBC)
2015-03-01
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doaj-27f85dea85744a3eb0225bc714a60c702020-11-24T23:46:45ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702015-03-01104320220810.5935/abc.20140188S0066-782X2015000300005Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable AnginaWeverton Ferreira LeiteJosé Antonio Franchini RamiresLuiz Felipe Pinho MoreiraCélia Maria Cassaro StrunzJosé Armando MangioneBackground: High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. Objective: To assess the correlation between serum hs-CRP levels (mg/L) in a peripheral vein in the left forearm (LFPV) with those in the coronary sinus (CS) of patients with coronary artery disease (CAD) and a diagnosis of stable angina (SA) or unstable angina (UA). Methods: This observational, descriptive, and cross-sectional study was conducted at the Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, and at the Hospital Beneficência Portuguesa de Sao Paulo, where CAD patients referred to the hospital for coronary angiography were evaluated. Results: Forty patients with CAD (20 with SA and 20 with UA) were included in the study. Blood samples from LFPV and CS were collected before coronary angiography. Furthermore, analysis of the correlation between serum levels of hs-CRP in LFPV versus CS showed a strong linear correlation for both SA (r = 0.993, p < 0.001) and UA (r = 0.976, p < 0.001) and for the entire sample (r = 0.985, p < 0.001). Conclusion: Our data suggest a strong linear correlation between hs-CRP levels in LFPV versus CS in patients with SA and UA.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015000300005&lng=en&tlng=enProteína C-ReativaDoença da Artéria CoronarianaAngina EstávelAngina InstávelSeio Coronário |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Weverton Ferreira Leite José Antonio Franchini Ramires Luiz Felipe Pinho Moreira Célia Maria Cassaro Strunz José Armando Mangione |
spellingShingle |
Weverton Ferreira Leite José Antonio Franchini Ramires Luiz Felipe Pinho Moreira Célia Maria Cassaro Strunz José Armando Mangione Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina Arquivos Brasileiros de Cardiologia Proteína C-Reativa Doença da Artéria Coronariana Angina Estável Angina Instável Seio Coronário |
author_facet |
Weverton Ferreira Leite José Antonio Franchini Ramires Luiz Felipe Pinho Moreira Célia Maria Cassaro Strunz José Armando Mangione |
author_sort |
Weverton Ferreira Leite |
title |
Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina |
title_short |
Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina |
title_full |
Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina |
title_fullStr |
Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina |
title_full_unstemmed |
Correlation between C-Reactive Protein in Peripheral Vein and Coronary Sinus in Stable and Unstable Angina |
title_sort |
correlation between c-reactive protein in peripheral vein and coronary sinus in stable and unstable angina |
publisher |
Sociedade Brasileira de Cardiologia (SBC) |
series |
Arquivos Brasileiros de Cardiologia |
issn |
1678-4170 |
publishDate |
2015-03-01 |
description |
Background: High sensitivity C-reactive protein (hs-CRP) is commonly used in clinical practice to assess cardiovascular risk. However, a correlation has not yet been established between the absolute levels of peripheral and central hs-CRP. Objective: To assess the correlation between serum hs-CRP levels (mg/L) in a peripheral vein in the left forearm (LFPV) with those in the coronary sinus (CS) of patients with coronary artery disease (CAD) and a diagnosis of stable angina (SA) or unstable angina (UA). Methods: This observational, descriptive, and cross-sectional study was conducted at the Instituto do Coração, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, and at the Hospital Beneficência Portuguesa de Sao Paulo, where CAD patients referred to the hospital for coronary angiography were evaluated. Results: Forty patients with CAD (20 with SA and 20 with UA) were included in the study. Blood samples from LFPV and CS were collected before coronary angiography. Furthermore, analysis of the correlation between serum levels of hs-CRP in LFPV versus CS showed a strong linear correlation for both SA (r = 0.993, p < 0.001) and UA (r = 0.976, p < 0.001) and for the entire sample (r = 0.985, p < 0.001). Conclusion: Our data suggest a strong linear correlation between hs-CRP levels in LFPV versus CS in patients with SA and UA. |
topic |
Proteína C-Reativa Doença da Artéria Coronariana Angina Estável Angina Instável Seio Coronário |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015000300005&lng=en&tlng=en |
work_keys_str_mv |
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