Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics

Recent evidence has extensively demonstrated the anticancer potential of nutraceuticals, including plant polyphenols. Polymeric nanocarrier systems have played an important role in improving the physicochemical and pharmacological properties of polyphenols, thus ameliorating their therapeutic effect...

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Main Authors: Umeorah Ernest, Hai-Yan Chen, Ming-Jun Xu, Yasamin Davatgaran Taghipour, Muhammad Hassham Hassan Bin Asad, Roja Rahimi, Ghulam Murtaza
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/11/2787
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spelling doaj-2801d0a5ff844159be2372a80d457a9f2020-11-25T00:15:26ZengMDPI AGMolecules1420-30492018-10-012311278710.3390/molecules23112787molecules23112787Anti-Cancerous Potential of Polyphenol-Loaded Polymeric NanotherapeuticsUmeorah Ernest0Hai-Yan Chen1Ming-Jun Xu2Yasamin Davatgaran Taghipour3Muhammad Hassham Hassan Bin Asad4Roja Rahimi5Ghulam Murtaza6Department of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, ChinaDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, ChinaDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, ChinaDepartment of Medical Nanotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 1416663547, IranDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus 22060, PakistanDepartment of Traditional Pharmacy, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran 5165665931, IranDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus 54600, PakistanRecent evidence has extensively demonstrated the anticancer potential of nutraceuticals, including plant polyphenols. Polymeric nanocarrier systems have played an important role in improving the physicochemical and pharmacological properties of polyphenols, thus ameliorating their therapeutic effectiveness. This article summarizes the benefits and shortcomings of various polymeric systems developed for the delivery of polyphenols in cancer therapy and reveals some ideas for future work.https://www.mdpi.com/1420-3049/23/11/2787cancer therapeuticspolymeric carriersnanoparticlespolyphenolscell lines
collection DOAJ
language English
format Article
sources DOAJ
author Umeorah Ernest
Hai-Yan Chen
Ming-Jun Xu
Yasamin Davatgaran Taghipour
Muhammad Hassham Hassan Bin Asad
Roja Rahimi
Ghulam Murtaza
spellingShingle Umeorah Ernest
Hai-Yan Chen
Ming-Jun Xu
Yasamin Davatgaran Taghipour
Muhammad Hassham Hassan Bin Asad
Roja Rahimi
Ghulam Murtaza
Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
Molecules
cancer therapeutics
polymeric carriers
nanoparticles
polyphenols
cell lines
author_facet Umeorah Ernest
Hai-Yan Chen
Ming-Jun Xu
Yasamin Davatgaran Taghipour
Muhammad Hassham Hassan Bin Asad
Roja Rahimi
Ghulam Murtaza
author_sort Umeorah Ernest
title Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
title_short Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
title_full Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
title_fullStr Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
title_full_unstemmed Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics
title_sort anti-cancerous potential of polyphenol-loaded polymeric nanotherapeutics
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2018-10-01
description Recent evidence has extensively demonstrated the anticancer potential of nutraceuticals, including plant polyphenols. Polymeric nanocarrier systems have played an important role in improving the physicochemical and pharmacological properties of polyphenols, thus ameliorating their therapeutic effectiveness. This article summarizes the benefits and shortcomings of various polymeric systems developed for the delivery of polyphenols in cancer therapy and reveals some ideas for future work.
topic cancer therapeutics
polymeric carriers
nanoparticles
polyphenols
cell lines
url https://www.mdpi.com/1420-3049/23/11/2787
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AT haiyanchen anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
AT mingjunxu anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
AT yasamindavatgarantaghipour anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
AT muhammadhasshamhassanbinasad anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
AT rojarahimi anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
AT ghulammurtaza anticancerouspotentialofpolyphenolloadedpolymericnanotherapeutics
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