Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms.

The emergence of influenza drug resistance has become of particular interest as current planning for an influenza pandemic involves using massive amounts of antiviral drugs. We use semi-stochastic simulations to examine the emergence of drug resistant mutants during the course of a single infection...

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Bibliographic Details
Main Authors: Hana M Dobrovolny, Catherine A A Beauchemin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5503263?pdf=render

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