Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b
Abstract The neurobehavioral effects of paternal smoking and nicotine use have not been widely reported. In the present study, nicotine exposure induced depression in the paternal generation, but reduced depression and promoted hyperactivity in F1 offspring. While this intergenerational effect was n...
Main Authors: | Jingbo Dai, Zhaoxia Wang, Wangjie Xu, Meixing Zhang, Zijue Zhu, Xianglong Zhao, Dong Zhang, Dongsheng Nie, Lianyun Wang, Zhongdong Qiao |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-07920-3 |
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