Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE a...

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Main Authors: Hiroyuki Okada, Yoshifumi Iwamaru, Morikazu Imamura, Kohtaro Miyazawa, Yuichi Matsuura, Kentaro Masujin, Yuichi Murayama, Takashi Yokoyama
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-02-01
Series:Emerging Infectious Diseases
Subjects:
atypical bovine spongiform encephalopathy
cattle
L-type
prion
oral transmission
prions and related diseases
Online Access:https://wwwnc.cdc.gov/eid/article/23/2/16-1416_article
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spelling doaj-284a77f256944d9f8f77ae84c68c29eb2020-11-25T01:35:12ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-02-0123228428710.3201/eid2302.161416Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among CattleHiroyuki OkadaYoshifumi IwamaruMorikazu ImamuraKohtaro MiyazawaYuichi MatsuuraKentaro MasujinYuichi MurayamaTakashi YokoyamaTo determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.https://wwwnc.cdc.gov/eid/article/23/2/16-1416_articleatypical bovine spongiform encephalopathycattleL-typeprionoral transmissionprions and related diseases
collection DOAJ
language English
format Article
sources DOAJ
author Hiroyuki Okada
Yoshifumi Iwamaru
Morikazu Imamura
Kohtaro Miyazawa
Yuichi Matsuura
Kentaro Masujin
Yuichi Murayama
Takashi Yokoyama
spellingShingle Hiroyuki Okada
Yoshifumi Iwamaru
Morikazu Imamura
Kohtaro Miyazawa
Yuichi Matsuura
Kentaro Masujin
Yuichi Murayama
Takashi Yokoyama
Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
Emerging Infectious Diseases
atypical bovine spongiform encephalopathy
cattle
L-type
prion
oral transmission
prions and related diseases
author_facet Hiroyuki Okada
Yoshifumi Iwamaru
Morikazu Imamura
Kohtaro Miyazawa
Yuichi Matsuura
Kentaro Masujin
Yuichi Murayama
Takashi Yokoyama
author_sort Hiroyuki Okada
title Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_short Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_full Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_fullStr Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_full_unstemmed Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_sort oral transmission of l-type bovine spongiform encephalopathy agent among cattle
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2017-02-01
description To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.
topic atypical bovine spongiform encephalopathy
cattle
L-type
prion
oral transmission
prions and related diseases
url https://wwwnc.cdc.gov/eid/article/23/2/16-1416_article
work_keys_str_mv AT hiroyukiokada oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT yoshifumiiwamaru oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT morikazuimamura oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT kohtaromiyazawa oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT yuichimatsuura oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT kentaromasujin oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT yuichimurayama oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
AT takashiyokoyama oraltransmissionofltypebovinespongiformencephalopathyagentamongcattle
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