Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish
Zebrafish models are well-established tools for investigating the underlying mechanisms of diseases. Here, we identified cercosporamide, a metabolite from the fungus Ascochyta aquiliqiae, as a potent bone morphogenetic protein receptor (BMPR) type I kinase inhibitor through a zebrafish embryo phenot...
Main Authors: | Jelmer Hoeksma, Gerard C. M. van der Zon, Peter ten Dijke, Jeroen den Hertog |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2020-09-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/13/9/dmm045971 |
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