Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Introduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administratio...

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Main Authors: Montasir Junaid, Muhammad Sohail Halim, Maisam Abbas Shiraz Onali, Sadaf Qadeer, Hareem Usman Khan, Naeem Sultan Ali
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2020-01-01
Series:International Archives of Otorhinolaryngology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1684037
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spelling doaj-2850925ed0474b168247a4cd75e7b1ae2020-11-25T03:47:12ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642020-01-012401e62e6710.1055/s-0039-1684037Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical TrialMontasir Junaid0Muhammad Sohail Halim1Maisam Abbas Shiraz Onali2Sadaf Qadeer3Hareem Usman Khan4Naeem Sultan Ali5Department of Otolaryngology-Head and Neck Surgery, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudia ArabiaByers Eye Institute, Stanford University, Palo Alto, CA, United StatesDepartment of Otorhinolaryngology-Head and Neck Surgery, Jinnah Medical College and Hospital, Karachi, PakistanDepartment of Otorhinolaryngology-Head and Neck Surgery, Sir Syed College of Medical Sciences for girls, Karachi, PakistanDepartment of Cardiology, Shifa Intersternal Hospital, Islamabad, PakistanDepartment of Otolaryngology-Head and Neck Surgery, The Aga Khan Hospital, Dar-es-salaam, TanzaniaIntroduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administration of local anesthetics. Objective To evaluate the role of intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale (VAS) scores in achieving pain relief after tonsillectomy procedure Methods In this study, 180 patients were randomized to 1 of the 6 groups: bupivacaine infiltration, lidocaine infiltration, normal saline infiltration, bupivacaine packing, lidocaine packing, and normal saline packing. Pain caused by speaking, swallowing, and on rest was assessed using VAS at 4, 8, 12, 16 hours, and at discharge. Results Significant analgesia was obtained in patients who received bupivacaine infiltration and packing compared with placebo (p < 0.05). The majority of the study subjects had no postoperative complications, and patients receiving bupivacaine infiltration required less additional analgesics in the first 24 hours after surgery. Conclusion We advocate the use of bupivacaine infiltration or packing immediately following the procedure to achieve adequate postoperative analgesia.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1684037tonsillectomypainanalgesia
collection DOAJ
language English
format Article
sources DOAJ
author Montasir Junaid
Muhammad Sohail Halim
Maisam Abbas Shiraz Onali
Sadaf Qadeer
Hareem Usman Khan
Naeem Sultan Ali
spellingShingle Montasir Junaid
Muhammad Sohail Halim
Maisam Abbas Shiraz Onali
Sadaf Qadeer
Hareem Usman Khan
Naeem Sultan Ali
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
International Archives of Otorhinolaryngology
tonsillectomy
pain
analgesia
author_facet Montasir Junaid
Muhammad Sohail Halim
Maisam Abbas Shiraz Onali
Sadaf Qadeer
Hareem Usman Khan
Naeem Sultan Ali
author_sort Montasir Junaid
title Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
title_short Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
title_full Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
title_fullStr Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
title_full_unstemmed Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
title_sort intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale scores—a prospective, randomized, placebo-controlled, double-blind clinical trial
publisher Thieme Revinter Publicações Ltda.
series International Archives of Otorhinolaryngology
issn 1809-9777
1809-4864
publishDate 2020-01-01
description Introduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administration of local anesthetics. Objective To evaluate the role of intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale (VAS) scores in achieving pain relief after tonsillectomy procedure Methods In this study, 180 patients were randomized to 1 of the 6 groups: bupivacaine infiltration, lidocaine infiltration, normal saline infiltration, bupivacaine packing, lidocaine packing, and normal saline packing. Pain caused by speaking, swallowing, and on rest was assessed using VAS at 4, 8, 12, 16 hours, and at discharge. Results Significant analgesia was obtained in patients who received bupivacaine infiltration and packing compared with placebo (p < 0.05). The majority of the study subjects had no postoperative complications, and patients receiving bupivacaine infiltration required less additional analgesics in the first 24 hours after surgery. Conclusion We advocate the use of bupivacaine infiltration or packing immediately following the procedure to achieve adequate postoperative analgesia.
topic tonsillectomy
pain
analgesia
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1684037
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