Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
Introduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administratio...
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doaj-2850925ed0474b168247a4cd75e7b1ae2020-11-25T03:47:12ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642020-01-012401e62e6710.1055/s-0039-1684037Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical TrialMontasir Junaid0Muhammad Sohail Halim1Maisam Abbas Shiraz Onali2Sadaf Qadeer3Hareem Usman Khan4Naeem Sultan Ali5Department of Otolaryngology-Head and Neck Surgery, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudia ArabiaByers Eye Institute, Stanford University, Palo Alto, CA, United StatesDepartment of Otorhinolaryngology-Head and Neck Surgery, Jinnah Medical College and Hospital, Karachi, PakistanDepartment of Otorhinolaryngology-Head and Neck Surgery, Sir Syed College of Medical Sciences for girls, Karachi, PakistanDepartment of Cardiology, Shifa Intersternal Hospital, Islamabad, PakistanDepartment of Otolaryngology-Head and Neck Surgery, The Aga Khan Hospital, Dar-es-salaam, TanzaniaIntroduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administration of local anesthetics. Objective To evaluate the role of intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale (VAS) scores in achieving pain relief after tonsillectomy procedure Methods In this study, 180 patients were randomized to 1 of the 6 groups: bupivacaine infiltration, lidocaine infiltration, normal saline infiltration, bupivacaine packing, lidocaine packing, and normal saline packing. Pain caused by speaking, swallowing, and on rest was assessed using VAS at 4, 8, 12, 16 hours, and at discharge. Results Significant analgesia was obtained in patients who received bupivacaine infiltration and packing compared with placebo (p < 0.05). The majority of the study subjects had no postoperative complications, and patients receiving bupivacaine infiltration required less additional analgesics in the first 24 hours after surgery. Conclusion We advocate the use of bupivacaine infiltration or packing immediately following the procedure to achieve adequate postoperative analgesia.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1684037tonsillectomypainanalgesia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Montasir Junaid Muhammad Sohail Halim Maisam Abbas Shiraz Onali Sadaf Qadeer Hareem Usman Khan Naeem Sultan Ali |
spellingShingle |
Montasir Junaid Muhammad Sohail Halim Maisam Abbas Shiraz Onali Sadaf Qadeer Hareem Usman Khan Naeem Sultan Ali Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial International Archives of Otorhinolaryngology tonsillectomy pain analgesia |
author_facet |
Montasir Junaid Muhammad Sohail Halim Maisam Abbas Shiraz Onali Sadaf Qadeer Hareem Usman Khan Naeem Sultan Ali |
author_sort |
Montasir Junaid |
title |
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial |
title_short |
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial |
title_full |
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial |
title_fullStr |
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial |
title_full_unstemmed |
Intraoperative Use of Analgesics in Tonsillar Fossa and Postoperative Evaluation with Visual analogue Scale Scores—A Prospective, Randomized, Placebo-Controlled, Double-Blind Clinical Trial |
title_sort |
intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale scores—a prospective, randomized, placebo-controlled, double-blind clinical trial |
publisher |
Thieme Revinter Publicações Ltda. |
series |
International Archives of Otorhinolaryngology |
issn |
1809-9777 1809-4864 |
publishDate |
2020-01-01 |
description |
Introduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar administration of local anesthetics.
Objective To evaluate the role of intraoperative use of analgesics in tonsillar fossa and postoperative evaluation with visual analogue scale (VAS) scores in achieving pain relief after tonsillectomy procedure
Methods In this study, 180 patients were randomized to 1 of the 6 groups: bupivacaine infiltration, lidocaine infiltration, normal saline infiltration, bupivacaine packing, lidocaine packing, and normal saline packing. Pain caused by speaking, swallowing, and on rest was assessed using VAS at 4, 8, 12, 16 hours, and at discharge.
Results Significant analgesia was obtained in patients who received bupivacaine infiltration and packing compared with placebo (p < 0.05). The majority of the study subjects had no postoperative complications, and patients receiving bupivacaine infiltration required less additional analgesics in the first 24 hours after surgery.
Conclusion We advocate the use of bupivacaine infiltration or packing immediately following the procedure to achieve adequate postoperative analgesia. |
topic |
tonsillectomy pain analgesia |
url |
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1684037 |
work_keys_str_mv |
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