What is the evidence that tau pathology spreads through prion-like propagation?

What is the evidence that tau pathology spreads through prion-like propagation?

Abstract Emerging experimental evidence suggests that the spread of tau pathology in the brain in Tauopathies reflects the propagation of abnormal tau species along neuroanatomically connected brain areas. This propagation could occur through a “prion-like” mechanism involving transfer of abnormal t...

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Bibliographic Details
Main Authors: Amrit Mudher, Morvane Colin, Simon Dujardin, Miguel Medina, Ilse Dewachter, Seyedeh Maryam Alavi Naini, Eva-Maria Mandelkow, Eckhard Mandelkow, Luc Buée, Michel Goedert, Jean-Pierre Brion
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer's disease
tau
prion-like propagation
transmission
tauopathies
aggregation
Online Access:http://link.springer.com/article/10.1186/s40478-017-0488-7

Internet

http://link.springer.com/article/10.1186/s40478-017-0488-7

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