HORMONE REFRACTORY PROSTATE CANCER AND ITS DEVELOPMENT DURING ANTIANDROGEN THERAPY

<p><em>Mechanisms of development of hormone refractory prostate cancer currently not fully understood.</em></p><p><strong><em>Materials and methods: </em></strong><em>treatment results of 135 prostate cancer patients underwent subcapsular o...

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Bibliographic Details
Main Authors: S. A. Rakul, R. D. Galimov
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Onkourologiâ
Subjects:
Online Access:http://oncourology.abvpress.ru/index.php/oncur/article/view/345
Description
Summary:<p><em>Mechanisms of development of hormone refractory prostate cancer currently not fully understood.</em></p><p><strong><em>Materials and methods: </em></strong><em>treatment results of 135 prostate cancer patients underwent subcapsular orchiectomy.</em></p><p><strong><em>Results: </em></strong><em>hormone resistance registered at 38 (28.15%) patients, were sensitive to anti-androgenic therapy 97 (71.85%) patients. There are reliable differences between the probability of development of hormone refractory and the patient's age, disease stage and degree of tumor cell differentiation.</em></p><p><strong><em>Conclusion: </em></strong><em>с</em><em>linical developed, laboratory and pathomorphological criteria, the use of which may reliably predict the likelihood of hormone refractory patients with prostate cancer on the background of antiandrogenic treatment.</em></p>
ISSN:1726-9776
1996-1812