Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time.

Infection with hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and end-stage liver disease worldwide. The genetics of HCV infection in humans and the disease course of chronic hepatitis C are both remarkably variable. Although the response to interferon tre...

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Bibliographic Details
Main Authors: Hui Li, Austin L Hughes, Nazneen Bano, Susan McArdle, Stephen Livingston, Heike Deubner, Brian J McMahon, Lisa Townshend-Bulson, Rachel McMahan, Hugo R Rosen, David R Gretch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3088699?pdf=render