Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function
Neurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing neurological deficits after the development of these major neurological di...
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doaj-28a94391f3874063bb72e1c0d90894db2020-11-24T23:21:45ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312016-12-0120427628710.5213/inj.1632776.388628Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding FunctionMyung-Hoon Han0Eun-Hye Lee1Seong-Ho Koh2 Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea Department of Neurology, Hanyang University College of Medicine, Seoul, Korea Department of Neurology, Hanyang University College of Medicine, Seoul, KoreaNeurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing neurological deficits after the development of these major neurological disorders. In recent years, it has become accepted that adult neural stem cells located in the subventricular and subgranular zones have the ability to proliferate and differentiate in order to replace lost or damaged neural cells. There have been many limitations in the clinical application of both endogenous and exogenous neurogenesis for neurological disorders. However, many studies have investigated novel mechanisms in neurogenesis and have shown that these limitations can potentially be overcome with appropriate stimulation and various approaches. We will review concepts related to possible therapeutic strategies focused on the perspective of neurogenesis for the treatment of patients diagnosed with Alzheimer disease, Parkinson disease, and ischemic stroke based on current reports.http://www.einj.org/upload/pdf/inj-1632776-388.pdfAlzheimer DiseaseParkinson DiseaseStrokeNeurogenesisNeural Stem Cells |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Myung-Hoon Han Eun-Hye Lee Seong-Ho Koh |
spellingShingle |
Myung-Hoon Han Eun-Hye Lee Seong-Ho Koh Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function International Neurourology Journal Alzheimer Disease Parkinson Disease Stroke Neurogenesis Neural Stem Cells |
author_facet |
Myung-Hoon Han Eun-Hye Lee Seong-Ho Koh |
author_sort |
Myung-Hoon Han |
title |
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function |
title_short |
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function |
title_full |
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function |
title_fullStr |
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function |
title_full_unstemmed |
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function |
title_sort |
current opinion on the role of neurogenesis in the therapeutic strategies for alzheimer disease, parkinson disease, and ischemic stroke; considering neuronal voiding function |
publisher |
Korean Continence Society |
series |
International Neurourology Journal |
issn |
2093-4777 2093-6931 |
publishDate |
2016-12-01 |
description |
Neurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing neurological deficits after the development of these major neurological disorders. In recent years, it has become accepted that adult neural stem cells located in the subventricular and subgranular zones have the ability to proliferate and differentiate in order to replace lost or damaged neural cells. There have been many limitations in the clinical application of both endogenous and exogenous neurogenesis for neurological disorders. However, many studies have investigated novel mechanisms in neurogenesis and have shown that these limitations can potentially be overcome with appropriate stimulation and various approaches. We will review concepts related to possible therapeutic strategies focused on the perspective of neurogenesis for the treatment of patients diagnosed with Alzheimer disease, Parkinson disease, and ischemic stroke based on current reports. |
topic |
Alzheimer Disease Parkinson Disease Stroke Neurogenesis Neural Stem Cells |
url |
http://www.einj.org/upload/pdf/inj-1632776-388.pdf |
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